Kessler Foundation

This trial tests whether a structured memory training program, called Strategy-Based Training to Enhance Memory (STEM), can improve learning and recall in people with multiple sclerosis who report memory difficulties. Participants attend eight training sessions over four weeks an…

This trial tests whether a group-based memory training program, called the modified Story Memory Technique (mSMT), can improve memory and everyday functioning in people with traumatic brain injury (TBI). Participants attend twice-weekly sessions for five weeks, working on memory …

This study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than…

This pilot study tested whether a non-invasive treatment called extracorporeal shockwave therapy (ESWT) can safely reduce spasticity—muscle stiffness and spasms—in people with chronic spinal cord injury. Five participants received ESWT or a sham treatment, and researchers measure…

This study tested whether a single session of moderate cycling combined with virtual reality could improve processing speed in people with multiple sclerosis who have mild-to-moderate mobility disability. Twenty-three participants completed one bout of exercise while using differ…

This study tested whether methylphenidate, a drug used for ADHD, can reduce the mental exhaustion that affects up to 95% of people with multiple sclerosis. Thirty-six adults with MS took both the drug and a placebo for four weeks each, without knowing which they were getting. The…

This study investigates whether disease-modifying medications for relapsing-remitting multiple sclerosis (RRMS) can reduce cognitive fatigue—the tiredness that follows intense mental effort. Researchers will use functional MRI to measure brain activation in people starting either…

This study explores whether the medication Tysabri can reduce cognitive fatigue—the tiredness that comes after intense mental effort—in people with relapsing-remitting multiple sclerosis (RRMS). Researchers will compare brain activity, measured with functional MRI, between RRMS p…

This study looked at whether giving feedback after a delay, instead of immediately, helps people with Parkinson's disease learn better. Forty participants completed a computer task where they got either instant or 25-minute-delayed feedback. The goal was to see if delayed feedbac…

This study looked at whether a single session of moderate cycling, done in a lab, with a non-immersive virtual reality screen, or with a full immersive virtual reality headset, could improve thinking speed and multitasking in 24 adults with traumatic brain injury. Participants co…