Janssen Research & Development, Llc

This study tested whether adding a new drug called aticaprant to standard antidepressants could help prevent depression from coming back in people who had recently gotten better. It focused on people whose depression includes a severe loss of interest and pleasure in life. The tr…

This study tested whether adding an experimental drug called aticaprant to a person's current antidepressant could better treat major depression, specifically for people who struggle with severe anhedonia—the inability to feel pleasure. It involved 101 adults whose depression had…