Institut National De La Santé Et De La Recherche Médicale, France
Clinical trials sponsored by Institut National De La Santé Et De La Recherche Médicale, France, explained in plain language.
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Scientists test new nasal spray to stop whooping cough
⭐️ VACCINE ⭐️ CompletedThis study tested a new, higher-dose version of a nasal spray vaccine designed to prevent whooping cough. It involved 54 healthy adults to see if the spray was safe and if it triggered a good immune response. Researchers also checked if the vaccine's weakened bacteria could brief…
Phase: PHASE1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: ⭐️ VACCINE ⭐️
Last updated Apr 01, 2026 14:42 UTC
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Scientists test First-Ever vaccine to protect pregnant women from malaria
⭐️ VACCINE ⭐️ CompletedThis early-stage study tested the safety of a new vaccine designed to protect pregnant women from malaria. The trial involved 68 healthy adult women in France and Burkina Faso who received different doses of the experimental vaccine. Researchers monitored participants for side ef…
Phase: PHASE1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 30, 2026 14:33 UTC
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Scientists test new malaria shot in first human volunteers
⭐️ VACCINE ⭐️ CompletedThis early-stage study tested the safety and immune response of a new malaria vaccine candidate. It involved 66 healthy adults from Europe and Africa, some with prior exposure to malaria. Volunteers received three shots of the experimental vaccine with different immune-boosting a…
Phase: PHASE1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 30, 2026 14:29 UTC
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Can a flu shot protect transplant patients?
⭐️ VACCINE ⭐️ CompletedThis study tested the safety and effectiveness of an H1N1 flu vaccine in people who have received a kidney transplant. It involved 122 adult transplant recipients who were taking medications to suppress their immune systems. Researchers measured the body's immune response to the …
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 27, 2026 12:38 UTC
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Scientists test swine flu vaccine safety for expectant mothers
⭐️ VACCINE ⭐️ CompletedThis study tested a specific H1N1 flu vaccine in pregnant women to see if it safely triggered a protective immune response. It involved about 110 women who were between 22 and 32 weeks pregnant. Researchers gave two vaccine doses and monitored the women's health and immune system…
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 20, 2026 14:47 UTC
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Scientists test Single-Dose nasal spray to shield newborns from whooping cough
⭐️ VACCINE ⭐️ CompletedThis early-stage study tested the safety and immune response of a new, genetically modified whooping cough vaccine given as a single nasal spray. It involved 48 healthy adult male volunteers to see if the vaccine was well-tolerated and triggered an immune reaction. The ultimate g…
Phase: PHASE1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: ⭐️ VACCINE ⭐️
Last updated Feb 27, 2026 15:19 UTC
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New program teaches skills to control drinking, reduce harm
Disease control CompletedThis study tested an education program called 'Choizitaconso' designed to help people with alcohol use disorder. The program teaches practical skills to help participants reduce their drinking and the harms it causes, rather than focusing only on complete abstinence. Researchers …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Apr 01, 2026 21:56 UTC
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Stem cell shot aims to restore erections after prostate cancer
Disease control CompletedThis early-stage study tested whether injecting a patient's own bone marrow stem cells into the penis could help restore natural erections after prostate cancer surgery. The research involved 18 men who had developed erectile dysfunction following prostate removal. The main goals…
Phase: PHASE1, PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Apr 01, 2026 21:56 UTC
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Vaccine tested to stop parasite reinfection in kids
Disease control CompletedThis study tested whether a new vaccine, called Bilhvax, could help prevent children from getting sick again with urinary schistosomiasis, a parasitic infection. The trial involved 250 infected children aged 6-9 in Senegal. All children received the standard drug treatment (prazi…
Phase: PHASE3 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Apr 01, 2026 21:56 UTC
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Could a childhood vaccine calm adult eczema?
Disease control CompletedThis small study tested whether getting a measles vaccine could improve symptoms of moderate-to-severe eczema in adults. Researchers gave 20 adult participants either the real measles vaccine or a placebo shot. They then monitored changes in the participants' immune systems and e…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Common painkiller tested as early heart help for tiniest babies
Disease control CompletedThis large European study tested if giving acetaminophen (like Tylenol) as a preventive treatment in the first five days of life could help close a persistent blood vessel near the heart in extremely premature infants. The goal was to see if this early treatment could increase th…
Phase: PHASE2, PHASE3 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Can regular Check-Ins keep diabetes in check?
Disease control CompletedThis study tested whether regular follow-up visits with nurses and dietitians help people with type 2 diabetes manage their condition better. 398 patients received education on diet and exercise, then were split into two groups: one received check-ups every three months, and the …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Apr 01, 2026 14:40 UTC
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Zapping the brain to relearn hand movements after stroke
Disease control CompletedThis study tested two new brain stimulation techniques to help improve hand movement in people who have had a stroke. Researchers compared stimulating the brain while also providing visual cues or balance-related signals. The goal was to see if these paired techniques could help …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Diabetes drug tested to boost immune attack on liver cancer
Disease control CompletedThis small, early-stage study tested if a diabetes medication called sitagliptin is safe for liver cancer patients before surgery. The goal was to see if the drug could help the body's immune cells better target and fight the tumor. Fourteen patients took the drug for three weeks…
Phase: PHASE1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Quick test aims to save children from hidden TB
Disease control CompletedThis study tested a new approach to find tuberculosis (TB) in young children hospitalized with severe pneumonia in six high-risk countries. Researchers wanted to see if using a fast, sensitive test on easy-to-collect samples (like nasal fluid and stool) right when a child arrives…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Race to find better treatment for dangerous fungal infections in premature babies
Disease control CompletedThis study compared two antifungal medications (fluconazole and micafungin) for treating suspected or confirmed fungal infections in newborns, particularly premature infants. Researchers tested whether micafungin works as well as the current standard treatment while also studying…
Phase: PHASE2, PHASE3 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Hope for untreatable muscle disease: transplant drug shows promise
Disease control CompletedThis study tested whether rapamycin, a drug used in organ transplants, could help stabilize muscle strength in adults with inclusion body myositis—a progressive muscle disease that currently has no effective treatment. Forty-four participants were randomly assigned to receive eit…
Phase: PHASE2, PHASE3 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Schools test extra support to level the playing field for overweight teens
Disease control CompletedThis study tested a school-based program to help overweight and obese teenagers manage their weight. It aimed to see if providing extra support—like motivational interviews, cooking classes, and activity funding—to teens from less advantaged backgrounds could give them the same b…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New tool aims to ease tough pregnancy treatment choice
Disease control CompletedThis study tested a decision-making tool designed to help women with a less active ectopic pregnancy choose between medical treatment (methotrexate) and surgery. The tool was used by 109 women and their doctors across 16 hospitals in France. Researchers measured how helpful and c…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope for kids with severe arthritis: drug trial shows promise
Disease control CompletedThis study tested whether the drug anakinra could help children and young adults with a severe form of juvenile arthritis that wasn't controlled by steroid medications. For the first month, half the 24 participants received anakinra and half received a placebo, followed by 11 mon…
Phase: PHASE2, PHASE3 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Scientists test drug cocktail to slow debilitating nerve disease
Disease control CompletedThis study tested three different drugs to see if they could reduce the buildup of harmful cholesterol-related chemicals in people with a rare, inherited nerve disease called SPG5. The trial involved 12 adult patients who took the drugs for two months. The main goal was to see if…
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Scientists test genetic vaccine to reboot immune system against stubborn hepatitis b
Disease control CompletedThis early-stage study tested whether a new type of vaccine made from DNA could safely help the body's immune system fight chronic hepatitis B. It involved 10 patients whose infections had not responded to standard medications. The main goal was to check if the vaccine was safe a…
Phase: PHASE1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Hope in a pill: drug trial seeks to tame deadly ebola
Disease control CompletedThis study tested whether a drug called favipiravir could help people survive Ebola Virus Disease. It involved 126 patients in Guinea who received the oral drug. The main goal was to see if the treatment could lower the high death rate associated with Ebola, especially for those …
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Experimental oil shows promise for rare brain energy disorder
Disease control CompletedThis study tested whether a special dietary oil called triheptanoin could help people with GLUT1 deficiency syndrome, a rare genetic disorder where the brain struggles to get enough energy. Twenty patients over age 3 with confirmed genetic mutations and movement or seizure proble…
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Brain fuel tested for rare childhood paralysis disorder
Disease control CompletedThis small, completed study tested whether a special dietary oil called triheptanoin could help control the sudden, paralyzing attacks in people with Alternating Hemiplegia of Childhood (AHC). Researchers gave the oil or a placebo to 10 French patients aged 15 and older to see if…
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 12, 2026 13:50 UTC
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Doctors inject gene therapy directly into Children's brains to fight rare fatal disease
Disease control CompletedThis early-stage study tested a new gene therapy approach for children with a rare, severe brain disease called metachromatic leukodystrophy (MLD). Doctors injected a modified virus carrying a healthy gene directly into the brains of five young children (ages 6 months to 4 years)…
Phase: PHASE1, PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Disease control
Last updated Mar 02, 2026 15:21 UTC
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Scientists hunt for blood test to predict dangerous pregnancy conditions
Diagnosis CompletedThis study aimed to find a better way to predict serious pregnancy complications like pre-eclampsia and poor fetal growth. Researchers tested whether measuring a specific protein (EG-VEGF) in a pregnant person's blood between 14-18 weeks could serve as an early warning sign. The …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Apr 01, 2026 14:42 UTC
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New genetic testing could solve mystery of unexplained intellectual disability
Diagnosis CompletedThis study compared two approaches to genetic testing for intellectual disability. Researchers tested whether whole genome sequencing (analyzing all genetic material from both parents and child) could find more causes of intellectual disability than current standard tests. The st…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Apr 01, 2026 14:42 UTC
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Your phone could soon diagnose your sleep apnea
Diagnosis CompletedThis study tested whether a smartphone app called Apneal can accurately diagnose sleep apnea. Researchers compared the app's results against the standard overnight sleep test (polysomnography) in 491 adults. The goal was to see if the app could correctly categorize the severity o…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Mar 30, 2026 14:29 UTC
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New ultrasound tech maps brain activity in Real-Time during surgery
Diagnosis CompletedThis study tested a new, highly sensitive ultrasound method to create maps of active brain areas during surgery for brain tumors or lesions. The goal was to see if this new, real-time method could work as well as the current gold-standard mapping techniques used by surgeons. It i…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Mar 30, 2026 14:29 UTC
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Brain scan breakthrough could spot Parkinson's sooner
Diagnosis CompletedThis study tested whether a special brain scan (fMRI) could help diagnose Parkinson's disease earlier. Researchers scanned the brains of 23 newly diagnosed patients and healthy volunteers to see if a specific area involved in vision reacts differently. The goal was to find a new …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Mar 17, 2026 13:09 UTC
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Race against time: new tool aims to spot deadly TB in vulnerable kids
Diagnosis CompletedThis study aimed to create a faster, simpler way to diagnose tuberculosis (TB) in young children who are severely malnourished and hospitalized. Researchers in Uganda and Zambia tested a combination of easy-to-collect samples and scans to develop a scoring system. The goal was to…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Mar 17, 2026 13:09 UTC
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Laser beam could spot hidden heart risk without touch
Diagnosis CompletedThis study tested a new, non-contact laser device to measure artery stiffness, a key sign of heart disease risk, in people with high blood pressure. It compared the new laser method to older, more uncomfortable techniques. The goal was to see if the laser could be a simpler, more…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Mar 13, 2026 15:06 UTC
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Guiding hands: can navigators close the gap in cancer screening?
Prevention CompletedThis study tested whether assigning a 'patient navigator'—a helper who guides people through the healthcare system—could increase participation in colorectal cancer screening. It focused on people aged 50-74 in France who had not been getting screened, especially those in less pr…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Prevention
Last updated Apr 01, 2026 21:55 UTC
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French schools test new push to get teens HPV vaccine
Prevention CompletedThis study tested different combinations of school and doctor programs to see which best increased HPV vaccination rates among French adolescents aged 11-14. Over 30,000 teens across 90 towns participated. The programs included school education for teens and parents, doctor train…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Prevention
Last updated Mar 30, 2026 14:31 UTC
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French study tests if flu shot keeps adults out of the hospital
Prevention CompletedThis study aimed to measure how well the 2012-2013 seasonal flu vaccine worked to prevent hospitalizations in adults. Researchers in France compared vaccinated and unvaccinated adults who were hospitalized with flu-like symptoms. They tested patients to confirm who had the flu to…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Prevention
Last updated Mar 30, 2026 14:29 UTC
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Can a mix of exercise, brain games, and diet keep seniors walking?
Prevention CompletedThis study tested whether a personalized program combining physical activity, cognitive training, and nutritional advice could prevent older adults from losing their ability to walk and perform daily tasks. It involved 210 people aged 60+ who were starting to show signs of physic…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Prevention
Last updated Mar 05, 2026 14:00 UTC
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Massive french trial tests if a phone app can save lives from suicide
Prevention CompletedThis study tested whether promoting a free web and mobile app called StopBlues could help prevent suicide and reduce psychological distress in the general population. Over 100,000 adults in 42 French communities were involved. Researchers compared different ways of promoting the …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Prevention
Last updated Mar 04, 2026 15:30 UTC
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Can dance lessons ease the symptoms of Huntington's disease?
Symptom relief CompletedThis study aimed to see if regular dance practice could help people with Huntington's Disease. Researchers enrolled 53 participants, including patients and their caregivers, for 8 months of weekly dance workshops. They measured changes in movement control, self-awareness, brain s…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Brain pacemaker trial aims to help Parkinson's patients walk again
Symptom relief CompletedThis study tested whether deep brain stimulation targeting a specific walking-control area of the brain could improve gait and balance problems in people with advanced Parkinson's disease. Six participants with severe walking issues that didn't respond well to standard medication…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Morning coffee shows promise for rare movement disorder
Symptom relief CompletedThis small study explored whether caffeine might help reduce involuntary movements in people with ADCY5-related dyskinesia, a rare genetic movement disorder with no current treatment. Researchers interviewed 15 patients by phone about their experiences using caffeine for their sy…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Apr 01, 2026 14:40 UTC
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Two drainage methods tested for pregnancy discomfort
Symptom relief CompletedThis study compared two techniques for draining excess amniotic fluid (polyhydramnios) during pregnancy to relieve maternal discomfort. Researchers tested whether using a syringe or a continuous suction device worked better and was more comfortable for 80 pregnant women. The goal…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Mar 30, 2026 14:37 UTC
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Dietary oil trial offers hope for rare muscle disorder sufferers
Symptom relief CompletedThis study tested whether a special dietary oil called triheptanoin could help adults with McArdle disease exercise better. McArdle disease is a rare inherited condition that causes severe muscle pain, cramps, and fatigue during physical activity. Researchers gave 12 participants…
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Doctors test video games to help Parkinson's patients walk better
Symptom relief CompletedThis study tested whether a video game-based rehabilitation program could help improve walking and balance in people with Parkinson's disease. Researchers worked with 25 patients who had movement problems that didn't respond well to standard medications. They measured changes in …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Video games tested to help Parkinson's patients walk better
Symptom relief CompletedThis small study tested whether a video game-based rehabilitation program is practical and acceptable for people with Parkinson's disease who have ongoing walking and balance problems, despite having a deep brain stimulator. It involved 10 participants to see if they could and wo…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Can meditation calm anxiety and protect memory?
Symptom relief CompletedThis study tested whether an 8-week mindfulness course could reduce anxiety and improve mental wellbeing in older adults who are worried about their memory but still test normally. Researchers compared the mindfulness program to a health education course in 168 participants acros…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Zapping the spine to stop the shakes?
Symptom relief CompletedThis study tested whether a mild electrical current applied to the spine could help people with primary orthostatic tremor. Eighteen patients received either a real or a fake (sham) stimulation to see if the real treatment improved their ability to stand without support and reduc…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Symptom relief
Last updated Mar 23, 2026 15:17 UTC
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First french registry launched to map mysterious overgrowth conditions
Knowledge-focused CompletedThis study created France's first national registry to better understand rare genetic overgrowth disorders. Researchers collected information from 28 patients with conditions like CLOVES and Klippel-Trenaunay syndromes to learn how common these disorders are and how they affect p…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists map brain connections in rare movement disorders
Knowledge-focused CompletedThis study aimed to understand how two key brain areas—the basal ganglia and cerebellum—interact in people with specific genetic forms of dystonia, a movement disorder. Researchers compared brain scans from 104 participants, including patients with ADCY5 or PRRT2 gene mutations a…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Massive study tracks Zika's impact on unborn babies
Knowledge-focused CompletedThis study observed over 26,000 pregnant women during the 2016 Zika outbreak in French Caribbean territories. Researchers collected medical information through standard care to understand how Zika infection during pregnancy affects fetal development and birth outcomes. The goal w…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists scan brains to unlock why dystonia patients feel out of control
Knowledge-focused CompletedThis study aimed to understand how dystonia affects a person's sense of agency—the feeling of being in control of one's own movements. Researchers used brain scans (MRI) and computer-based thinking tests to compare 76 people with cervical or myoclonus dystonia to healthy voluntee…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Brain scans reveal Age's role in Alzheimer's protein buildup
Knowledge-focused CompletedThis study used brain imaging scans to understand how age affects the buildup of amyloid protein in the brains of people with Alzheimer's disease and related conditions. Researchers compared younger-onset and older-onset Alzheimer's patients, along with people having specific lan…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists probe gene link to heart health after eating
Knowledge-focused CompletedThis study aimed to understand how a specific gene variation affects how the body processes cholesterol after eating. Researchers compared 100 healthy men with two different versions of this gene. They took blood samples before and after a test meal to see if the gene variation c…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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Scientists map the Brain's 'Forget' button for bad memories
Knowledge-focused CompletedThis study aimed to understand how healthy young brains voluntarily suppress negative or unpleasant memories. Researchers used EEG brain scans and computer tasks to measure attention and brain activity while participants tried to block certain memories. The goal was to map the br…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists probe why thigh fat might be healthier than belly fat
Knowledge-focused CompletedThis study examined the cellular makeup of fat tissue in different body areas of healthy women. Researchers compared fat from the abdomen and thigh to understand why thigh fat might be less harmful to heart and metabolic health than abdominal fat. The study involved 20 women and …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists map brain energy in Huntington's patients
Knowledge-focused CompletedThis study aimed to understand how brain energy levels change at different stages of Huntington's disease. Researchers used specialized MRI scans to measure energy-related chemicals in the brains of 50 patients. The goal was to see if changes in brain energy correlate with diseas…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists scan brains to see how history shapes our memories
Knowledge-focused CompletedThis study aimed to understand how shared cultural knowledge, or 'collective memory,' influences how our brains form personal memories. Researchers used MRI brain scans on 24 healthy French volunteers while they performed memory tasks related to World War II. The goal was to map …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists probe why flu vaccines work better for some
Knowledge-focused CompletedThis study aimed to understand how well seasonal and H1N1 pandemic flu vaccines worked in hospital staff. Researchers measured the strength and type of immune response in 147 healthy volunteers, looking at how factors like age and past flu shots affected protection. The goal was …
Phase: PHASE4 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists probe Brain's role in movement disorder
Knowledge-focused CompletedThis study aimed to understand how a part of the brain called the cerebellum affects the brain's ability to adapt and learn new movements. Researchers compared 120 people, including healthy volunteers and patients with dystonia, a movement disorder. They used non-invasive brain s…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists scan brains to see if words can tame food cravings
Knowledge-focused CompletedThis study aimed to understand how a talking therapy called motivational interviewing might help people with food addiction. Researchers used brain scans (fMRI) to see how listening to one's own reasons for changing eating habits affects decision-making around food. They compared…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists scan brains to hunt for Huntington's clues
Knowledge-focused CompletedThis small study aimed to see if a potential treatment could improve how the brain uses energy in people with early Huntington's disease. Researchers used a special brain scan to measure energy levels before, during, and after a visual test. The goal was to gather information to …
Phase: PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists sniff out clues to bipolar disorder
Knowledge-focused CompletedThis study aimed to understand if there is a link between a person's sense of smell and bipolar disorder. Researchers compared smell test results and brain scans from 240 people with bipolar disorder to healthy volunteers. The goal was to gather information to help understand the…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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Parkinson's Patients' brains struggle to predict the future
Knowledge-focused CompletedThis study investigated how Parkinson's disease affects the brain's ability to anticipate when something will happen. Researchers compared eye movements and brain activity in 40 people—some with Parkinson's and some healthy—to understand how dopamine influences time expectation. …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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Scientists use High-Tech scans to peer inside Stroke-Damaged brain cells
Knowledge-focused CompletedThis study used advanced MRI scans to look closely at how water and brain chemicals move inside cells after a stroke. Researchers scanned 24 stroke patients and 24 healthy volunteers to understand the cellular damage and recovery process over three months. The goal was to gather …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists probe Skin's healing power in devastating blistering disease
Knowledge-focused CompletedThis study aimed to understand how skin cells from people with a severe, rare blistering skin disorder (RDEB) can heal wounds. Researchers took small skin samples from 30 patients to grow and test their cells in the lab. The goal was to gather essential knowledge to help design f…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists map the brain in rare movement disorder
Knowledge-focused CompletedThis study aimed to understand how myoclonus dystonia affects brain function related to thinking and emotions. Researchers compared brain scans from 47 people with the condition to healthy volunteers while they performed simple tasks. The goal was to identify differences in brain…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Landmark study tracks thousands of premature babies into childhood
Knowledge-focused CompletedThis study followed over 3,400 children in France who were born very early (before 35 weeks of pregnancy) to understand their long-term health and development. Researchers collected information from birth records, family questionnaires, and medical exams up to age 12. The goal is…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists grow 'Mini-Guts' to battle bowel disease
Knowledge-focused CompletedThis study aimed to create a new lab tool for developing future treatments. Researchers took tiny tissue samples from patients with inflammatory bowel disease (IBD) and healthy people during routine colonoscopies. They grew these samples into 3D 'mini-guts' (organoids) in the lab…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists scan brains to see how therapy fights OCD
Knowledge-focused CompletedThis study aimed to understand how two different types of cognitive behavioral therapy (CBT) change brain activity in people with obsessive compulsive disorder (OCD). Researchers scanned the brains of 35 adults with OCD before, during, and after 15 weeks of therapy to see which a…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Brain fog lingers after rare hormone disease is cured
Knowledge-focused CompletedThis study aimed to understand the lasting memory and thinking problems that can remain even after Cushing's disease is cured. Researchers compared 30 cured patients to healthy volunteers, using a new 3D computer game to test memory alongside standard questionnaires. The goal was…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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French study reveals how many frontline health workers had COVID-19 antibodies
Knowledge-focused CompletedThis study aimed to understand how many primary care health workers in France, like family doctors, pharmacists, and dentists, had been exposed to the COVID-19 virus by measuring antibodies in their blood. It also checked their household members. The goal was to gather data on in…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists zap brains to control breathing
Knowledge-focused CompletedThis study explored whether gentle electrical brain stimulation could change signals to the main breathing muscle (diaphragm). Researchers tested three types of stimulation on 12 healthy young men to see how they affected muscle responses. The goal was to gather basic knowledge t…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists hunt for the genetic secrets of periods
Knowledge-focused CompletedThis study aimed to understand why humans menstruate by comparing our genes to other primates. Researchers collected menstrual fluid from 21 healthy women to analyze which genes are active during a period. The goal was to learn about the evolution of menstruation, not to provide …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists track Body's natural defenses against colon cancer
Knowledge-focused CompletedThis study aimed to understand how the immune system responds to colon cancer by observing patients over time. Researchers collected blood and tissue samples from 100 adults with colon adenocarcinoma to track immune cell activity. The study did not test treatments but followed pa…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists search for clues in rare skin disorder
Knowledge-focused CompletedThis French study aimed to better understand Netherton syndrome, a rare genetic skin condition. Researchers followed 18 people with the disease to learn how it naturally progresses over time and how it affects the immune system. The goal was to identify new biological targets tha…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists use earthquake tech to peer inside bones
Knowledge-focused CompletedThis study tested a new ultrasound method to see and measure blood flow inside bones, which current machines cannot do. Researchers adapted techniques from earthquake science to create images of blood moving in the bone and marrow of healthy volunteers. The goal is to gain knowle…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Could a simple pee test tell if chemo is working?
Knowledge-focused CompletedThis study aimed to see if a new, non-invasive urine test could help monitor how well chemotherapy is working for people with advanced colorectal cancer. Researchers collected urine and saliva samples from 16 patients before and after starting chemotherapy. They measured specific…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists map Brain's blood flow in rare genetic disorder
Knowledge-focused CompletedThis study aimed to better understand CADASIL, a rare genetic condition that affects blood vessels in the brain. Researchers used MRI and EEG brain scans on 60 participants to see how blood flow and brain cell activity are connected in people with this disease. The goal was to ga…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists hunt for Autism's genetic roots
Knowledge-focused CompletedThis study aimed to understand the genetic causes of autism spectrum disorders. Researchers analyzed DNA from over 1,600 people with autism to look for specific gene changes that affect how brain cells communicate. The goal was to build knowledge that could help guide future rese…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists test 10 drugs at once to map your Body's chemical processing
Knowledge-focused CompletedThis study aimed to understand how healthy people's bodies process and break down a combination of ten different drugs. Ten healthy volunteers took the drugs to help researchers map individual differences in drug metabolism. The goal was to gather basic safety data and learn how …
Phase: PHASE1 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists track eyes to unlock Autism's social puzzle
Knowledge-focused CompletedThis study aimed to understand social challenges in autism by observing how children look at pictures. Researchers used eye-tracking technology to measure where 150 children, some with autism and some without, focused their gaze on faces and human movements. The goal was to ident…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists track hidden health legacy of ebola survivors
Knowledge-focused CompletedThis study aimed to better understand the long-term health of people who survived Ebola and the people they lived with. Researchers followed 787 survivors and their household contacts in the Democratic Republic of the Congo for over a year. They tracked health problems, immune sy…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists hunt for genetic clues in thousands of Parkinson's patients
Knowledge-focused CompletedThis study aimed to understand how specific gene mutations contribute to Parkinson's disease. Researchers collected blood samples and genetic data from 2,934 people, including patients with Parkinson's and healthy family members. The goal was to create a detailed catalog of mutat…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists scan brains to unlock secrets of collective memory
Knowledge-focused CompletedThis French study used brain scans to explore how shared cultural knowledge shapes personal memories. Researchers scanned 27 healthy adults while they recalled a visit to a WWII memorial, comparing brain activity patterns with analysis of French media about WWII. The goal was to …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Scientists hunt for blood test to predict antidepressant success
Knowledge-focused CompletedThis study aimed to find biological markers that could predict who will respond well to the antidepressant venlafaxine. Researchers followed 60 people with major depression and 20 healthy volunteers for three months. They measured specific proteins in the blood and linked them to…
Phase: PHASE4 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC
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Scientists map the genetic blueprint of liver cancer
Knowledge-focused CompletedThis study aimed to better understand the genetic and molecular characteristics of liver cancer (hepatocellular carcinoma). Researchers analyzed tumor samples from 808 patients to identify common genetic patterns and test a 'liquid biopsy' method using blood samples. The goal was…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC
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Wearable sensors track dementia Patients' daily motivation
Knowledge-focused CompletedThis small pilot study tested whether wearable sensors could measure apathy (loss of motivation) in people with frontotemporal dementia during everyday activities. Researchers compared 14 participants—some with dementia and some healthy—to see if sensors could detect patterns of …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC
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Scientists map brain activity to predict coma recovery
Knowledge-focused CompletedThis French study aimed to understand how brain networks change as coma patients regain consciousness. Researchers followed 43 brain-injured coma patients, performing MRI brain scans and clinical assessments at one and two months after injury. The goal was to identify brain activ…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Hidden outbreak: scientists test homeless shelters for COVID-19
Knowledge-focused CompletedThis study aimed to understand how widespread COVID-19 infections were among homeless people and staff in three Paris shelters after outbreaks occurred there. Researchers tested 179 residents and workers for antibodies to see who had been infected, especially since many might not…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Researchers track H1N1 Flu's impact on pregnant women and newborns
Knowledge-focused CompletedThis study aimed to understand how common H1N1 flu infections were in pregnant women and what effects the virus had on both the mother and the pregnancy outcome. It followed 919 pregnant women in three Paris maternity hospitals during the pandemic period. The research also looked…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC
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Scientists scan brains to unlock the mystery of ALS walking difficulties
Knowledge-focused CompletedThis study aimed to understand why people with ALS have trouble starting to walk and maintaining balance. Researchers compared 59 people with and without ALS, using brain scans (fMRI) and detailed movement tests. The goal was to map how the brain controls movement in ALS to guide…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:03 UTC
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Scientists track Cancer's daily rhythm through urine
Knowledge-focused CompletedThis study aimed to understand if certain markers in urine follow daily patterns in people with metastatic colorectal cancer. Researchers collected urine samples from 32 participants (half with cancer, half healthy) over two days to measure these patterns. The goal was to gather …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Scientists probe lungs of critically ill flu patients
Knowledge-focused CompletedThis study aimed to better understand why some people get very sick from H1N1 flu. Researchers analyzed fluid from the lungs of 30 patients who were so ill they needed a ventilator in the intensive care unit. By studying the virus and the body's immune response in the lungs, they…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Researchers map breathing troubles in advanced MS patients
Knowledge-focused CompletedThis study aimed to understand and describe breathing problems in people with severe multiple sclerosis. Researchers observed 70 patients with advanced MS to measure their breathing function during sleep and while awake. The goal was to gather information about how MS affects bre…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Life after the ventilator: tracking the hidden scars of severe flu
Knowledge-focused CompletedThis study followed people who survived a life-threatening lung injury from the 2009 H1N1 flu. Researchers compared two groups: those who needed a special life-support machine and those who did not. They checked lung function, quality of life, and mental health to understand the …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:29 UTC
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Scientists map hidden gut bacteria in search for diabetes clues
Knowledge-focused CompletedThis French research study aimed to understand the role of gut bacteria in obesity and type 2 diabetes. Researchers collected and analyzed bacteria samples from the small intestine and colon of 90 participants, including people with obesity, obesity plus diabetes, and a control g…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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French study maps long road for ventilated stroke survivors
Knowledge-focused CompletedThis French study followed 364 stroke patients who needed breathing machines in intensive care. Researchers tracked their recovery for one year to understand how many regain independence versus face severe disability. The goal is to gather better information to help doctors and f…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Scientists hunt blood clues to predict deadly brain bleed complication
Knowledge-focused CompletedThis study aimed to understand why some people develop a dangerous complication called vasospasm after a brain bleed from a burst aneurysm. Researchers collected daily blood samples from 89 patients to look for genetic markers that might predict who is at risk. The goal was to ga…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Scans reveal how childhood cancer treatment affects young minds
Knowledge-focused CompletedThis study aimed to understand how radiation therapy for childhood brain tumors affects memory and thinking skills later in life. Researchers used MRI brain scans and memory tests on 60 young survivors who had completed treatment at least five years earlier. The goal was to see h…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Hidden COVID spread in hospitals revealed by mali study
Knowledge-focused CompletedThis study aimed to understand how COVID-19 spread through hospitals in Bamako, Mali. Researchers tested 450 hospitalized patients and healthcare workers for current infection and past immunity. The goal was to track transmission patterns, identify asymptomatic cases, and study v…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Massive french study tracks COVID's hidden spread
Knowledge-focused CompletedThis study aimed to understand how many people in France had been infected with COVID-19 by testing blood samples from nearly 100,000 participants. It also looked at how social factors, health behaviors, and preventive measures affected infection rates. The goal was to gather kno…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Scientists map the brain to find source of Tourette's impulsivity
Knowledge-focused CompletedThis study aimed to understand the brain basis of impulsive thoughts and actions in people with Tourette syndrome. Researchers used MRI brain scans and behavioral tests on 80 adults with Tourette's and 40 healthy volunteers. The goal was to identify specific brain connections lin…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Scientists scan brains to see how surgery rewires facial paralysis
Knowledge-focused CompletedThis study aimed to understand how the brain changes after surgery for severe facial paralysis. Researchers used a special, non-invasive brain scanner (MEG) on 16 patients before and after their facial surgery. They measured brain activity while patients made facial movements and…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC
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Scientists search for early warning signs in ALS
Knowledge-focused CompletedThis study aimed to understand how nerve cells in the spinal cord communicate in ALS (amyotrophic lateral sclerosis). Researchers compared electrical activity in the spinal nerves of 101 healthy people and recently diagnosed ALS patients. The goal was to find measurable signs (bi…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Scientists hunt for the sudden death gene
Knowledge-focused CompletedThis study aimed to understand if certain genes make people more likely to experience sudden cardiac arrest. Researchers analyzed DNA from over 2,000 people who had an out-of-hospital cardiac arrest. The goal was to find genetic markers that could help doctors identify and protec…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC
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Scientists zap brains to unlock secrets of walking
Knowledge-focused CompletedThis study aimed to understand how two specific brain areas help us keep our balance when we start walking. Researchers temporarily reduced activity in these brain areas in 20 healthy volunteers using safe magnetic stimulation. They then measured how this affected the volunteers'…
Phase: PHASE1, PHASE2 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC
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Scientists map the brain to uncover ALS's hidden sensory side
Knowledge-focused CompletedThis study aimed to understand the origin of subtle sensory changes in people with Amyotrophic Lateral Sclerosis (ALS). Researchers used brain imaging and electrical activity recordings to see how ALS affects brain function related to touch and sensation. The goal was to gather k…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:40 UTC
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French pilot paves way for faster cancer gene tests
Knowledge-focused CompletedThis study tested whether a new system for analyzing a patient's tumor genes could work fast enough to help doctors choose treatments. It involved 24 adults with advanced colorectal cancer or soft-tissue sarcoma. The main goal was to see if the complex process of gene sequencing …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:40 UTC
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Scientists scan brains to unlock secrets of traumatic memories
Knowledge-focused CompletedThis study aimed to understand how the brain processes traumatic memories and why some people develop Post-Traumatic Stress Disorder (PTSD). Researchers followed survivors of the 2015 Paris terrorist attacks, along with a comparison group, using brain scans and psychological test…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:24 UTC
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Scientists map hidden brain vessels in hunt for headache cure
Knowledge-focused CompletedThis study aimed to understand the cause of idiopathic intracranial hypertension (IIH), a rare condition that causes severe headaches and vision problems in young women. Researchers used a special high-resolution MRI technique to compare tiny drainage vessels in the brain lining …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:06 UTC
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Brain scans reveal how autism alters attention to emotions and new information
Knowledge-focused CompletedThis study aimed to understand how the brains of people with Autism Spectrum Disorder (ASD) automatically pay attention to emotional information and new changes in their environment. Researchers compared 120 children and adults with ASD to healthy volunteers using brain scans (EE…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:06 UTC
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Scientists map how dementia affects Brain's thinking center
Knowledge-focused CompletedThis research study aimed to understand how the brain's frontal lobe works during thinking tasks like categorization and analogical reasoning. Researchers compared brain activity in 130 participants—some with frontal dementia conditions and some healthy volunteers—using cognitive…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:05 UTC
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Surgery rewires taste buds: study probes why patients crave less fat
Knowledge-focused CompletedThis study aimed to understand why people eat less fatty and sugary foods after weight-loss surgery. Researchers examined 50 obese patients before and six months after surgery to see if the operation changed their taste buds and how they perceive fat. They collected tiny samples …
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:51 UTC
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Do your Mother's broken bones predict your future? science investigates
Knowledge-focused CompletedThis study aimed to understand how bone structure and fracture risk might be inherited from mothers to daughters. Researchers compared bone scans and health markers between daughters whose mothers had experienced bone fractures and those whose mothers had not. The goal was to ide…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:50 UTC
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Scientists hunt for clues in the brain to unlock future treatments for rare movement disorders
Knowledge-focused CompletedThis study aimed to find better ways to measure the progression of two rare, inherited brain diseases called Spinocerebellar Ataxia Type 2 and Type 7. Researchers followed 40 people with these conditions for one year, using brain scans, blood tests, and movement assessments. The …
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:50 UTC
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Scientists test DIY blood tests on Zero-Gravity flights
Knowledge-focused CompletedThis study tested whether a simple finger-prick blood test could work in zero gravity. Healthy volunteers on special 'vomit comet' flights tried to collect their own blood samples after drinking caffeine. The goal is to develop better tools for monitoring how astronauts' bodies p…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:50 UTC
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Scientists test if yawning holds clue to epilepsy
Knowledge-focused CompletedThis small, completed study aimed to understand how a brain chemical called dopamine works in people with a common form of epilepsy. Researchers compared 31 people with epilepsy to healthy volunteers, giving them a low dose of a dopamine-stimulating drug or a placebo. They then m…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:24 UTC
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Scientists probe the Brain's 'Self-Knowledge' switch in dementia
Knowledge-focused CompletedThis study aimed to understand why some people with Alzheimer's or frontotemporal dementia lose awareness of their own condition, a symptom called anosognosia. Researchers studied 77 participants, including patients and healthy older adults, using brain scans and EEG tests to mea…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:28 UTC
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Scientists gather baby blood to unlock future sickle cell cure
Knowledge-focused CompletedThis study collected umbilical cord blood from newborns at risk for sickle cell disease to use in laboratory experiments. Researchers aimed to study these cells to develop future gene therapy methods. The study involved 44 participants and did not provide direct treatment to part…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:25 UTC
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Scientists track eye movements to unlock brain secrets in movement disorders
Knowledge-focused CompletedThis study aimed to understand how the brain controls movement by comparing eye movements in different patient groups. Researchers tracked eye movements in 14 participants with dystonia, essential tremor, Parkinson's disease, and healthy volunteers. The goal was to see if differe…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:23 UTC