Insmed Incorporated

This study tested an inhaled medication called treprostinil palmitil (TPIP) in 102 adults with pulmonary arterial hypertension (PAH), a condition where high blood pressure in the lungs makes it hard to breathe and exercise. The goal was to see if TPIP could lower resistance in lu…

This study tested a once-daily pill called brensocatib in 1,767 adults with non-cystic fibrosis bronchiectasis, a lung condition that causes chronic cough and frequent infections. The goal was to see if the drug could reduce the number of serious lung flare-ups over one year comp…

This study tested a new inhaled antibiotic (ALIS) added to standard oral antibiotics for adults newly diagnosed with a chronic lung infection caused by MAC bacteria. The goal was to see if the combination improved breathing symptoms more than standard treatment alone. 425 partici…

This study checked the long-term safety of an inhaled powder drug (treprostinil palmitil) in 31 people with pulmonary hypertension caused by interstitial lung disease. Participants had already completed a previous study of the same drug. The main goal was to see how many had side…

This study tested a new oral tablet called brensocatib in adults with cystic fibrosis. Researchers wanted to understand how the drug moves through the body and check its safety over a 4-week period. The trial involved 29 participants who took either the drug or a placebo, and it …

This study tested an experimental drug called brensocatib in 288 adults with chronic sinusitis (sinus swelling) who do not have nasal polyps. Participants took either 10 mg, 40 mg, or a placebo daily for 24 weeks. The goal was to see if the drug improves daily symptoms like stuff…

This study looked at how two different versions of an inhaled drug (called TPIP) are absorbed by the body. 42 healthy adults took single doses of each version. The goal was to see which version delivers the drug more consistently, which helps design better treatments for the futu…