Insilico Medicine Hong Kong Limited

This study tests an experimental pill called ISM5411 (Garutadustat) in 80 adults with active ulcerative colitis. Half receive the drug, half a placebo, and neither patients nor doctors know who gets what. The goal is to check if the drug is safe and helps control the disease.

This early-phase study tests a new drug called ISM3412 in people with advanced solid tumors that have a specific genetic change (MTAP deletion). The main goals are to check the drug's safety and find the best dose. About 80 participants will take part in two stages: first to find…

This early-stage trial is testing a new oral drug called ISM6331 in 100 adults with advanced mesothelioma or other solid tumors that have not responded to standard treatments. The study aims to find a safe dose and check for any early signs that the drug can shrink tumors. Partic…

This study tests an experimental oral drug called INS018_055 in 40 adults with idiopathic pulmonary fibrosis (IPF), a disease that causes lung scarring and breathing difficulty. The main goal is to check the drug's safety over 12 weeks. Participants will be randomly assigned to r…

This Phase 1 trial is testing the safety and tolerability of a new drug called ISM8969 in healthy adults and obese adults at risk of heart disease. About 100 participants will receive either the drug or a placebo. The study aims to see how the body processes the drug and if it ca…