Dualitybio Inc.

This study tests a new drug called DB-1324 in people with advanced or spreading stomach, bowel, or other gastrointestinal cancers that have stopped responding to standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumor…

This study tests two new drug combinations (DB-1311 with BNT327 or DB-1305) in 450 adults with advanced or metastatic solid tumors that have not responded to other treatments. The main goals are to check safety and see if the drugs shrink tumors. Participants must be in fairly go…

This study tests a new drug called DB-1310 in people with advanced solid tumors that have stopped responding to standard treatments. The goal is to find a safe dose and see if the drug can shrink tumors. About 1,000 adults will take part in two phases: first to check safety, then…

This early-stage study tests an experimental drug, DB-1303/BNT323, in people with advanced solid tumors that have a protein called HER2. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. About 796 participants will take part across mul…

This study tests a new injection called DB-2304 in healthy people and those with lupus (SLE or CLE). The main goal is to check safety and side effects. About 148 adults will take part. This is an early-stage trial to see if the drug is safe enough for further testing.

This study tests an experimental drug called DB-1311/BNT324 in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors. About 862 adults will take pa…

This study tests a new experimental drug, DB-1419, in adults with advanced or metastatic solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About 360 participants will ta…

This early-phase study tests a new drug called DB-1317 in about 233 adults with advanced solid tumors that have worsened after standard treatments. The goal is to find a safe dose and see if the drug can shrink tumors. Participants will receive the drug intravenously and be monit…