Brain tumor trial delivers targeted toxin directly into tumors
Disease control
Completed
This phase 1 study tested a drug called D2C7-IT in 81 adults with recurrent malignant glioma (a type of brain tumor). The drug is a lab-made antibody linked to a toxin that targets specific proteins on tumor cells. It was infused directly into the tumor over 72 hours using thin t…
Phase: PHASE1 • Sponsor: Darell Bigner • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC