Darell Bigner
Clinical trials sponsored by Darell Bigner, explained in plain language.
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Brain tumor virus therapy takes on chemo in Head-to-Head trial
Disease control Recruiting nowThis trial compares a virus-based treatment called lerapolturev to the chemotherapy drug lomustine in adults with recurrent glioblastoma, an aggressive brain cancer. Lerapolturev is injected directly into the tumor and later under the skin around the neck lymph nodes to stimulate…
Phase: PHASE2 • Sponsor: Darell Bigner • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Experimental brain tumor cocktail targets recurrent glioma
Disease control Recruiting nowThis early-phase trial tests a combination of two drugs—D2C7-IT and 2141-V11—for adults with recurrent malignant glioma, a serious brain cancer. The drugs are delivered directly into the tumor and nearby lymph areas. The main goal is to check safety and find the right dose in 90 …
Phase: PHASE1 • Sponsor: Darell Bigner • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Brain cancer breakthrough? new immunotherapy combo targets recurrent glioblastoma
Disease control Recruiting nowThis early-stage trial is testing a combination of two immunotherapy drugs, D2C7-IT and 2141-V11, for people with recurrent glioblastoma, a fast-growing brain cancer. The treatment is delivered directly into the brain after surgery, followed by injections near the neck to boost t…
Phase: PHASE1 • Sponsor: Darell Bigner • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Experimental brain cancer cocktail shows promise in early trial
Disease control Recruiting nowThis study tests two experimental immunotherapy drugs, D2C7-IT and 2141-V11, in adults with a newly diagnosed, aggressive type of brain cancer called glioblastoma. The drugs are given directly into the brain after surgery, followed by injections near the neck lymph nodes. The goa…
Phase: PHASE1, PHASE2 • Sponsor: Darell Bigner • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC