Experimental brain cancer cocktail shows promise in early trial
NCT ID NCT05734560
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two experimental immunotherapy drugs, D2C7-IT and 2141-V11, in adults with a newly diagnosed, aggressive type of brain cancer called glioblastoma. The drugs are given directly into the brain after surgery, followed by injections near the neck lymph nodes. The goal is to see if this combination is safe and helps patients live longer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
D2C7-IT and 2141-V11 (immunotherapy drugs)
What this could lead to
If successful, this could lead to a new treatment option that extends survival for people with a hard-to-treat brain cancer.
What could go wrong
This is an early-phase trial with only 50 participants, so results may not apply to everyone. The drugs are experimental and could cause serious side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••