Centre Hospitalier Universitaire De Besancon

This study looks at whether a treatment called extracorporeal photopheresis can help kidney transplant recipients whose bodies are rejecting the new organ. The treatment involves filtering the patient's blood, treating it with a light-activated drug, and returning it to the body.…

This study tests a new drug, MP0317, combined with standard chemotherapy and immunotherapy for people with advanced bile duct cancer that cannot be removed by surgery. The goal is to see if this combination helps keep the cancer from growing for at least 12 months. About 75 adult…

This study tests whether adding a cancer vaccine (UCPVax) to standard immunotherapy (atezolizumab and bevacizumab) can shrink tumors better than standard therapy alone in people with advanced liver cancer that cannot be removed by surgery. About 105 adults who have not had prior …

This study is testing a new blood test to quickly identify people who may have colorectal cancer. It aims to help doctors decide who needs urgent care, especially when colonoscopy appointments are delayed. The study will include 400 adults who either had a positive stool test or …

This study aims to find blood-based biomarkers that can distinguish malignant pancreatic lesions from benign ones. Researchers will analyze blood samples from 100 adults with benign pancreatic conditions and compare them to existing data from patients with pancreatic cancer. The …

This study tests whether a supervised exercise program can improve sleep in people with alcohol use disorder. Forty adults with sleep problems will take part in activities like walking, cycling, and yoga. Researchers will track sleep quality, melatonin levels, and how well partic…

This study aims to find biological markers that can predict how well liver cancer patients respond to a combination of two immunotherapy drugs, tremelimumab and durvalumab. Researchers will follow 120 adults with advanced liver cancer who have not had prior systemic treatment. Th…

This study aims to see if it's practical to measure sleep in adults who play video games regularly but don't have gaming disorder. Forty participants (gamers and non-gamers) will keep sleep and gaming diaries, wear a wrist monitor, and provide urine samples for melatonin testing.…