Celldex Therapeutics

This study is testing whether an investigational drug called barzolvolimab can safely reduce severe itching and improve skin in adults with moderate to severe atopic dermatitis (eczema). About 131 participants will receive either the drug at one of two doses or a placebo via inje…

This study is testing whether a new drug called barzolvolimab can safely reduce hives and itching in adults with chronic spontaneous urticaria (CSU) whose symptoms are not controlled by standard allergy medicines. About 976 participants will receive either the study drug or a pla…

This study is testing an investigational drug called barzolvolimab for adults with chronic spontaneous urticaria, a condition causing long-lasting, itchy hives. It is for people whose hives are not well-controlled even with standard antihistamine medications. The main goal is to …

This study is testing an investigational drug called barzolvolimab to see if it can safely reduce severe itching and improve skin lesions in adults with prurigo nodularis. About 140 participants will receive either the drug or a placebo via injection every four weeks for 24 weeks…

This is a very early study to check if a new drug called CDX-622 is safe for people. It will be tested in 85 healthy volunteers who do not have the conditions the drug is meant to treat. Researchers will give different doses to see how the body handles the drug and watch for any …