Barbara Ann Karmanos Cancer Institute

This pilot study is testing whether a device called TheraBionic P1, which delivers targeted electromagnetic fields, can affect breast cancer tumors before surgery. About 24 women with early-stage, hormone receptor-positive, HER2-negative breast cancer will use the device three ti…

This study tests whether adding a non-invasive device that delivers low-level radio waves (AM RF EMF) to the targeted drug fruquintinib can help people with metastatic colorectal cancer that has stopped responding to other treatments live longer. About 102 participants will recei…

This study tests a device called TheraBionic P1 in people with advanced liver cancer who have already tried at least two other treatments or cannot take standard therapy. The goal is to see if the device can help them live longer and improve their quality of life. About 198 adult…

This study tests whether adding a device that delivers amplitude-modulated radiofrequency electromagnetic fields (Therabionic P1) to standard chemotherapy (gemcitabine and nab-paclitaxel) can help control metastatic pancreatic cancer. About 30 adults with advanced pancreatic canc…

This early-phase study tests whether adding metformin (a common diabetes drug) to standard chemotherapy or immunotherapy is safe for people with advanced solid tumors. About 60 participants will take metformin alone for two weeks, then continue it alongside their regular cancer t…

This early study tests a special PET/CT scan that uses a modified tryptophan molecule to make tumors light up more clearly than normal tissue. About 24 adults with brain, breast, neuroendocrine, or rectal cancers will get one scan to see if this method helps doctors tell tumors a…

This study tests a new tattoo ink called Magic Ink, which is only visible under ultraviolet light, for guiding daily radiation treatments in breast cancer patients. Researchers want to see if it is as safe and easy to use as standard tattoo ink. Thirty women with early-stage brea…

This study looks at whether a high-intensity CrossFit program can improve movement, strength, and quality of life in cancer survivors better than standard exercise guidelines. About 500 adult cancer survivors will take part in a 13-week program. Researchers will measure changes i…

This study is testing a culturally tailored online program to help African American cancer survivors understand and pursue genetic counseling and testing. Researchers will work with community leaders and genetic experts to adapt the program and see if it increases testing uptake.…