Agenus Inc.

This study tests whether adding a new immunotherapy drug called botensilimab to standard chemotherapy works better than chemotherapy alone for people with metastatic pancreatic cancer that has worsened after initial treatment. About 81 participants will be randomly assigned to on…

This study tests a new drug called botensilimab, alone or with another drug, in 150 adults with advanced melanoma that no longer responds to standard immunotherapy. The goal is to see if the drug can shrink tumors or slow the cancer's growth. Participants must have had prior anti…

This early-phase study tests two experimental immunotherapy drugs (botensilimab and balstilimab) in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the best dose. About 499 participants with various can…

This phase 2 study tests two experimental immunotherapy drugs, botensilimab alone or combined with balstilimab, against standard chemotherapy options for people with advanced colorectal cancer that has stopped responding to previous treatments. The goal is to see if these drugs c…