Aft Pharmaceuticals, Ltd.

This study tests if a rapamycin cream, applied after laser treatment, can improve the appearance of port wine stain birthmarks more than a placebo cream. About 30 children aged 10 or younger with facial, neck, or upper trunk birthmarks will apply the cream daily for 12 weeks. The…

This study tests whether a new combination painkiller (Combogesic 325, which mixes ibuprofen and acetaminophen) works better than acetaminophen alone for teens aged 12 to 17 recovering from orthopedic surgery. About 180 teens will be randomly assigned to one of three groups, taki…

This study tests an IV medicine called Combogesic IV, which combines ibuprofen and acetaminophen, in children aged 2 to 17 with acute pain. The goal is to see how the body handles the drug and if it is safe. About 60 children will receive the medicine every 6 hours for up to 5 da…