XEROSTOMIA

This early-stage study tests whether injecting a person's own bone marrow stem cells into their salivary glands is safe and tolerable for treating severe dry mouth after radiation for head and neck cancer. About 23 adults who finished radiation at least two years ago and have no …

This study tested whether Crest Daily Whitening Serum can reduce dry mouth and perceived bad breath in 27 adults with chronic dry mouth. Participants used the product for one week and reported their symptoms. The goal was symptom relief, not a cure.

This study aimed to see if using MRI scans to guide radiation therapy could better protect saliva glands and reduce dry mouth in people with oropharynx cancer. It planned to compare standard radiation planning with MRI-guided planning. However, the study was withdrawn before enro…

This study tests whether a toothpaste with arginine can improve dry mouth (xerostomia) by changing saliva acidity and mouth bacteria. About 70 adults with dry mouth caused by medications will use the toothpaste for 3 months. Researchers will measure saliva pH and oral microbiome …

This study follows 100 head and neck cancer patients receiving standard radiotherapy to see how their teeth, gums, and saliva change over time. Researchers measure gum health, tooth condition, and quality of life before and after treatment. The goal is to better understand long-t…