WRINKLES

This pilot study compares two FDA-approved cosmetic procedures—fractional laser and high-intensity focused ultrasound—for treating wrinkles around the eyes (crow's feet and lower eyelid lines). About 20 adults aged 35–60 with moderate wrinkles will receive one treatment on each s…

This completed clinical trial tested a high-intensity focused ultrasound (HIFU) device called ULTRAFORMER MPT for lifting eyebrows without surgery. 180 adults aged 20-65 with mild to moderate forehead skin laxity received either a single HIFU treatment or no treatment. The study …

This study tested a new device that uses radiofrequency energy to tighten skin and reduce wrinkles on the face and around the eyes. 284 adults received one treatment session and were followed for 3 months. The goal was to see if the new device works as well as an existing device,…

This study tested a new radiofrequency device called 10THERMA to see if it works as well as a current device for reducing mild-to-moderate wrinkles around the eyes and cheeks. 80 adults received one treatment and were followed for 16 weeks. The goal was to see if the new device i…

This study looked at the safety and performance of RefillHA Volume, a dermal filler used to smooth facial wrinkles and add volume. It involved 78 adults who wanted wrinkle correction. Researchers tracked side effects and how well the filler worked in everyday clinic use.

This study tested whether taking collagen supplements daily for 16 weeks can improve skin density, reduce wrinkles, and enhance skin texture in healthy women aged 40 to 65. Participants took either a placebo or one of four collagen-based supplements. The goal was to see if these …

This study tested a device that uses red, infrared, and blue LED light plus vibration to improve skin health. 115 adults aged 35-65 used the device daily for 12 weeks. Researchers measured changes in fine lines, wrinkles, skin tone, and firmness using expert grading and imaging.