WOUND HEALING

This trial compares two ways to manage the wound after surgical removal of a chronic pilonidal sinus. Half of the 200 participants will receive a negative pressure wound therapy (NPWT) dressing that applies gentle suction to the wound, while the other half will receive standard o…

This study tests whether a vacuum dressing (negative pressure wound therapy) reduces infection compared to standard bandages after skin graft surgery for leg tumors. About 242 adults will be randomly assigned to one of the two dressings. The main goal is to see if the vacuum dres…

This study tests whether OROXID®, a mouthwash that releases oxygen bubbles, can help gums heal better after wisdom tooth removal or similar surgery. Sixty adults will use the mouthwash or standard care for 14 days. Researchers will check for signs like redness, swelling, and woun…

This study tests a silk-based wound dressing against a standard adhesive dressing in 50 adults undergoing double-incision mastectomy for female-to-male gender affirmation. Each patient serves as their own control, with one side of the chest getting the silk dressing and the other…

This study tests whether a cold plasma device applied during and after thyroid surgery can speed up wound healing and reduce pain and infection. About 26 adults having their thyroid removed will be randomly assigned to get either standard wound care or the plasma treatment. Resea…

This study tests a gel called Nano Bio Fusion (NBF) to see if it helps heal wounds on the roof of the mouth after gum graft surgery. About 36 adults will apply either the NBF gel or a placebo gel four times a day for four weeks. Researchers will measure wound size, pain, and infl…

This study tests a hydrocolloid dressing (a special bandage) applied right after oculofacial surgery to see if it can replace antibiotic ointment. Twenty adults who have had Mohs surgery or other facial reconstruction will wear the dressing for one week. The goal is to simplify p…

This study tests whether a closed incision negative pressure wound therapy (ciNPWT) device can reduce wound complications after breast reduction surgery. 92 women will have one breast treated with the device and the other with standard adhesive strips. The goal is to see if the d…

This study is checking if a special collagen wound dressing called HealiAid is safe for people who have had breast tumor surgery. About 60 adults aged 18-70 with small breast tumors (benign or malignant) will receive the dressing right after their tumor is removed. Researchers wi…

This study follows 100 people with advanced gum disease (Stage III or IV) who undergo regenerative periodontal surgery. Researchers track how the surgical site heals in the first one to two weeks and then check whether that early healing pattern relates to gum health and bone cha…

This study looks at whether a harmless thermal camera can help doctors see how surgical wounds are healing after skin surgery. About 120 adults having skin lesions removed will have their wounds photographed with the camera. The goal is to catch problems like infection or slow he…

This study looks at how different laser energy levels affect skin damage and repair. Twenty healthy Chinese women will receive various laser doses on their forearms. Researchers will track changes in skin color, moisture, and healing over 10 days. The goal is to create a model fo…

This observational study follows 30 women undergoing DIEP flap breast reconstruction after mastectomy. Researchers will measure inflammation and oxidative stress markers in blood samples taken before and after surgery. The goal is to understand how the body responds to the tempor…

This study looks at how the jawbone changes right after a tooth is pulled and a bone graft is placed. Researchers want to see if the bone expands or stays the same right after extraction, and how that affects bone width and height four months later. The goal is to better understa…