WILMS TUMOR

This early-phase study is testing a new type of cell therapy called AGAR T cells in children and young adults with solid tumors that have come back or haven't responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and…

This study is testing a targeted drug called selpercatinib in children and young adults with advanced or returning cancers that have specific changes in a gene called RET. The goal is to see if the drug can shrink tumors and control the cancer's growth. Participants take the drug…

This study is testing whether a pill called cabozantinib can help control rare cancers that have come back or stopped responding to other treatments in children and young adults. It includes patients with sarcomas, Wilms tumor, and other rare tumors. The drug aims to slow or stop…

This early-stage study is testing a new type of personalized cell therapy for children and young adults whose solid tumors have come back or haven't responded to other treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack cance…

This study is testing a drug called ensartinib in children and young adults whose advanced cancers have specific genetic changes (ALK or ROS1). The goal is to see if the drug can shrink tumors or stop them from growing in patients whose cancer has come back or hasn't responded to…

This study is testing an oral drug called ulixertinib in children and adolescents whose advanced cancers have not responded to standard treatments and have a specific genetic change in a cell pathway called MAPK. The main goal is to see if the drug can shrink tumors and control t…

This early-stage study is testing a new type of treatment called CATCH T cells in adults with advanced solid tumors that have a specific marker (GPC3). Doctors take a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer, and then infu…

This study is testing a personalized approach for children and young adults with advanced cancers that have come back or stopped responding to standard treatments. Doctors first test the genetic makeup of a patient's tumor to look for specific changes. If a matching change is fou…

This early-phase study is testing the safety and feasibility of a new treatment called CAR T-cell therapy for children and young adults whose solid tumors have come back or not responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to be…

This study is testing a drug called ivosidenib in children and young adults (ages 1-21) whose cancers have returned or not responded to standard treatments. The drug is given as a daily pill and is designed to specifically block cancer growth in tumors that have a particular gene…

This study is testing a drug called erdafitinib in children and young adults with advanced cancers that have returned or not responded to standard treatments. It is for patients whose tumors have specific genetic changes (FGFR mutations). The goal is to see if the drug, which is …