VASO-OCCLUSIVE CRISIS
Clinical trials for VASO-OCCLUSIVE CRISIS explained in plain language.
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New drug cuts painful sickle cell crises in major trial
Disease control CompletedThis study tested a drug called inclacumab in 241 people with sickle cell disease who often have painful vaso-occlusive crises. Participants received either the drug or a placebo, and researchers tracked how many crises occurred over 48 weeks. The goal was to see if inclacumab co…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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Could pressurized oxygen ease sickle cell pain?
Symptom relief CompletedThis study looked at whether breathing pure oxygen in a high-pressure chamber (hyperbaric oxygen therapy) can reduce pain and shorten hospital stays for adults having a sickle cell pain crisis. Eight adults with uncomplicated pain crises received 1 to 3 sessions of this therapy. …
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Jun 16, 2026 12:51 UTC
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Laughing gas may ease sickle cell pain without opioids
Symptom relief CompletedThis small study tested nitrous oxide (laughing gas) to relieve severe pain in children with sickle cell disease during a pain crisis. Five children aged 8 to 18 who still had high pain after standard treatment received nitrous oxide. Researchers measured pain relief right after …
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE2 • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 15, 2026 19:09 UTC