VASO-OCCLUSIVE CRISIS
Clinical trials for VASO-OCCLUSIVE CRISIS explained in plain language.
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New drug cuts painful sickle cell crises in major trial
Disease control CompletedThis study tested a drug called inclacumab in 241 people with sickle cell disease aged 12 and older. The goal was to see if it could reduce the number of painful vaso-occlusive crises (VOCs) over 48 weeks compared to a placebo. Participants received either the drug or a placebo, …
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 17, 2026 04:36 UTC
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Could pressurized oxygen ease sickle cell pain?
Symptom relief CompletedThis study looked at whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help adults with sickle cell disease who are having a painful crisis. Eight adults received 1-3 sessions, each about two hours long. Researchers measured pain levels before…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Laughing gas may ease sickle cell pain when morphine fails
Symptom relief CompletedThis study tested nitrous oxide (laughing gas) as a pain reliever for children aged 8 to 18 with sickle cell disease who were having a severe pain crisis. The goal was to see if it could quickly lower pain when standard treatments like morphine were not enough. Only 5 participant…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE2 • Sponsor: Columbia University • Aim: Symptom relief
Last updated May 06, 2026 16:14 UTC