VASO-OCCLUSIVE CRISIS
Clinical trials for VASO-OCCLUSIVE CRISIS explained in plain language.
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New drug aims to cut sickle cell pain episodes
Disease control CompletedThis study tested a drug called inclacumab in about 240 people with sickle cell disease who experience painful vaso-occlusive crises. Participants received either inclacumab or a placebo by IV infusion. The main goal was to see if inclacumab could reduce the number of these painf…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Could laughing gas replace opioids for sickle cell pain?
Symptom relief CompletedThis small study tested whether nitrous oxide (laughing gas) can quickly relieve severe pain in children with sickle cell disease during a pain crisis. Five patients aged 8 to 18 who still had high pain after standard treatment received nitrous oxide in the emergency room. Resear…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: PHASE2 • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could pressurized oxygen ease sickle cell pain?
Symptom relief CompletedThis study tested whether hyperbaric oxygen therapy — breathing pure oxygen in a pressurized chamber — could reduce pain and hospital stays for adults having a sickle cell pain crisis. Eight adults with uncomplicated crises received 1 to 3 sessions. Researchers measured pain chan…
Matched conditions: VASO-OCCLUSIVE CRISIS
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC