UROTHELIAL CARCINOMA BLADDER

This was a planned Phase 3 study testing a drug called NDV-01 (a slow-release combination of two chemotherapy drugs) for people with a type of bladder cancer that did not respond to standard BCG treatment. The goal was to see if the drug could make the cancer disappear, but the s…

This early-stage study tests an experimental drug called BL-M17D1 in 120 adults with advanced solid tumors that have a specific protein (HER2) or a HER2 gene change. The main goals are to check the drug's safety, find the right dose, and see if it shrinks tumors. Participants mus…

This study tests a new approach for people with muscle-invasive bladder cancer who cannot receive standard chemotherapy. The treatment combines an immunotherapy drug (sasanlimab) with targeted radiation to help the body's immune system fight the tumor before surgery. The goal is …

This study tests a new drug, UGN-103, placed directly into the bladder to treat a common type of bladder cancer that hasn't spread deep into the bladder wall. About 99 people with low-grade, intermediate-risk bladder cancer will receive the treatment. The main goal is to see if t…

This study was designed to test if a new drug called NDV-01 could keep bladder cancer from returning after surgery. It was for people with intermediate-risk non-muscle invasive bladder cancer. However, the trial was withdrawn before enrolling any participants, so no results are a…

This study tests a combination of two chemotherapy drugs, gemcitabine and docetaxel, given directly into the bladder for people with early-stage bladder cancer who have not received standard BCG therapy. The goal is to see if this treatment can clear the cancer and keep it from c…

This early-phase study tests an experimental drug called RNDO-564, alone or with pembrolizumab, in adults with advanced solid tumors (like bladder, lung, or breast cancer) that have stopped responding to standard treatments. The main goals are to check safety, find the best dose,…

This study looks at a urine test called Bladder CARE Assay to see if it can accurately detect bladder cancer in people whose standard tests (cystoscopy or cytology) were not clear. About 80 adults with suspicious but inconclusive results will provide a urine sample before their n…

This study collects tumor tissue from about 416 people with various advanced cancers to develop and train a new diagnostic platform called Elephas. The goal is to see how accurately the platform can predict whether a patient will respond to immunotherapy, compared to standard met…