UROLOGIC CANCER

This program provides early access to cretostimogene grenadenorepvec, a virus-based therapy, for patients with non-muscle invasive bladder cancer that has not responded to standard BCG treatment. Eligible participants have a specific type of bladder cancer (CIS with or without hi…

This study tests a behavioral program to help women who have had pelvic radiation use vaginal dilators more regularly. Dilators can prevent or treat vaginal narrowing that makes exams or sex painful. 88 women will be randomly assigned to either the program (with coping strategies…

This study will enroll 200 adults aged 60 or older who are scheduled for major surgery for urologic cancer. Researchers want to see if an artificial intelligence analysis of a standard heart test (ECG) taken before surgery can predict whether a patient will suffer heart injury or…

This study tests two navigation systems—3D Slicer and Siemens Monaco—to help surgeons locate and remove abnormal lymph nodes during urologic cancer surgery. The goal is to see if these image-guided tools make the procedure simpler and more precise. Twenty adults with suspected or…

This study looks at how well different fluids (albumin and Ringer's solution) increase blood volume during laparoscopic surgery. About 60 adults having abdominal surgery will receive one of three fluid types. The goal is to see which fluid keeps the heart and blood vessels workin…

This study is testing whether tiny particles in the blood, called extracellular vesicles, can predict nerve damage caused by chemotherapy. Researchers will follow 120 adults with various cancers who are receiving specific chemo drugs. Participants give blood samples and answer qu…

This study is testing a web-based application that lets cancer patients report side effects from radiation therapy in real time. The goal is to see if this tool helps doctors spot and address complications sooner. About 30 patients with gynecologic, urologic, or breast cancer wil…