TP53 GENE MUTATION
Clinical trials for TP53 GENE MUTATION explained in plain language.
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New hope for aggressive leukemia? drug combo targets tough genetic mutation
Disease control Not yet recruitingThis early-stage study tests a new drug called axatilimab added to standard chemotherapy for people with a specific, high-risk form of acute myeloid leukemia (AML) that has a TP53 mutation or deletion. The goal is to find the safest dose of axatilimab and see how well the combina…
Matched conditions: TP53 GENE MUTATION
Phase: PHASE1 • Sponsor: Northside Hospital, Inc. • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope for tough liver cancers: triple therapy targets gene mutation
Disease control Not yet recruitingThis study tests a combination of three drugs—firsekibart, tislelizumab, and lenvatinib—in 25 adults with advanced liver cancer that has a TP53 gene mutation and has not responded to previous immunotherapy. The goal is to see if the combination can shrink tumors and control the d…
Matched conditions: TP53 GENE MUTATION
Phase: NA • Sponsor: Tongji Hospital • Aim: Disease control
Last updated Apr 29, 2026 15:04 UTC