TOTAL NEOADJUVANT TREATMENT
Clinical trials for TOTAL NEOADJUVANT TREATMENT explained in plain language.
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Rectal cancer breakthrough: could a new drug combo save your rectum?
Disease control Recruiting nowThis study tests whether a combination of chemotherapy and radiation (total neoadjuvant therapy, or TNT) can shrink rectal tumors enough so that some patients can avoid surgery and instead be monitored closely. About 400 adults with early-stage rectal cancer will be randomly assi…
Matched conditions: TOTAL NEOADJUVANT TREATMENT
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New combo therapy before surgery shows promise for tough esophageal cancer
Disease control Recruiting nowThis study tests a new approach for people with locally advanced esophageal cancer. Participants first receive a combination of immunotherapy and chemotherapy, then chemoradiation, followed by surgery. The goal is to see if this sequence can shrink tumors more effectively and imp…
Matched conditions: TOTAL NEOADJUVANT TREATMENT
Phase: PHASE2 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New combo therapy aims to boost rectal cancer remission
Disease control Recruiting nowThis study is for people with locally advanced rectal cancer that hasn't spread. It tests whether adding an immunotherapy drug (PD-1 inhibitor) to a standard treatment plan (short-course radiation plus chemotherapy and targeted therapy) can lead to a complete disappearance of the…
Matched conditions: TOTAL NEOADJUVANT TREATMENT
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC