TOTAL NEOADJUVANT TREATMENT
Clinical trials for TOTAL NEOADJUVANT TREATMENT explained in plain language.
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New combo therapy aims to shrink rectal tumors before surgery
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (PD-1 inhibitor) to a standard treatment plan (short-course radiation, chemotherapy, and a targeted therapy) can improve outcomes for people with locally advanced rectal cancer. About 104 participants will receive the standard…
Matched conditions: TOTAL NEOADJUVANT TREATMENT
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 16, 2026 23:51 UTC
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New combo therapy aims to shrink esophageal tumors before surgery
Disease control Recruiting nowThis study tests whether giving a combination of immunotherapy and chemotherapy, followed by chemoradiation, before surgery can improve outcomes for people with locally advanced esophageal cancer. The goal is to shrink the tumor and reduce the chance of the cancer coming back. Ab…
Matched conditions: TOTAL NEOADJUVANT TREATMENT
Phase: PHASE2 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated May 16, 2026 23:37 UTC
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Breakthrough trial may let rectal cancer patients keep their rectum without surgery
Disease control Recruiting nowThis study tests whether a combination of chemotherapy and radiation before surgery (total neoadjuvant therapy) can help about half of rectal cancer patients achieve a complete response, allowing them to avoid surgery and preserve their rectum through a watch-and-wait strategy. T…
Matched conditions: TOTAL NEOADJUVANT TREATMENT
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos • Aim: Disease control
Last updated May 15, 2026 11:56 UTC