T2DM
Clinical trials for T2DM explained in plain language.
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Diabetes drug semaglutide under scrutiny for bone risks
Disease control Not yet recruitingThis study looks at whether semaglutide, a common diabetes drug, affects bone density and fracture risk in people with type 2 diabetes. Researchers will compare semaglutide plus metformin to metformin alone over 12 months in 150 adults aged 50-75. The goal is to see if the drug's…
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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Triple-Drug cocktail targets diabetes and fatty liver in new trial
Disease control Not yet recruitingThis study tests whether adding alogliptin to a standard two-drug therapy (pioglitazone and metformin) improves blood sugar, cholesterol, and pancreas function in people with type 2 diabetes who also have fatty liver disease. About 80 adults who have not used diabetes drugs in th…
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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New diabetes pill HRS9531 enters Mid-Stage trial
Disease control Not yet recruitingThis study tests whether a new tablet, HRS9531, can help control blood sugar in people with type 2 diabetes. About 240 adults who have not achieved good blood sugar control with lifestyle changes or metformin will receive either the study drug or a placebo for 20 weeks. The main …
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 15, 2026 19:01 UTC
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New drug aims to protect kidneys in diabetes patients
Disease control Not yet recruitingThis study tests whether the investigational drug HTD1801 can slow kidney damage in adults with both type 2 diabetes and chronic kidney disease. About 75 participants will take either HTD1801 or a placebo twice daily for 12 weeks. The main goal is to see if the drug reduces prote…
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 12, 2026 12:08 UTC
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Sleep and menopause may harm diabetic women's hearts, study warns
Knowledge-focused Not yet recruitingThis study looks at how menopause and poor sleep change heart structure and function in women aged 48-58 with type 2 diabetes. Researchers will use heart ultrasounds to measure early signs of heart strain. No treatment is given; the goal is to better understand these risks.
Matched conditions: T2DM
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated May 18, 2026 12:04 UTC