SUBSTANCE ABUSE
Clinical trials for SUBSTANCE ABUSE explained in plain language.
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New hope for pregnant women battling opioid addiction: monthly shot vs daily pill
Disease control CompletedThis study tested whether a once-monthly injection of buprenorphine works as well as daily pills to treat opioid use disorder in 140 pregnant women. The goal was to see if the monthly shot could reduce illicit opioid use during pregnancy and after birth. Results help doctors choo…
Matched conditions: SUBSTANCE ABUSE
Phase: PHASE3 • Sponsor: T. John Winhusen, PhD • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New study tests better ways to link former inmates to HIV and addiction treatment
Disease control CompletedThis study tested two different approaches to help people recently released from jail or prison get connected to care for HIV, hepatitis C, STIs, and opioid use disorder. Over 600 adults took part. The goal was to see which method worked better for starting and staying on treatme…
Matched conditions: SUBSTANCE ABUSE
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Prizes for parents: can small rewards keep teens out of trouble?
Disease control CompletedThis study tested whether giving caregivers prize draws for attending court hearings, treatment sessions, and probation meetings could reduce substance use and delinquency in teens already in juvenile drug court. Fifty-three teens aged 13-17 and their caregivers took part. The go…
Matched conditions: SUBSTANCE ABUSE
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Probation officers as drug counselors: a new way to help teens?
Disease control CompletedThis study looked at whether juvenile probation officers can deliver a behavioral program called Contingency Management to teens on their caseload who have drug problems. The program uses rewards and counseling to encourage teens to stop using drugs. Researchers measured drug use…
Matched conditions: SUBSTANCE ABUSE
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Can a school program stop teens from misusing pills?
Prevention CompletedThis study tested a program for high school students to prevent misuse of prescription drugs like painkillers and sedatives. Over 1,800 teens participated in either the program or standard classes. The program used online lessons and group activities to change attitudes and build…
Matched conditions: SUBSTANCE ABUSE
Phase: NA • Sponsor: National Health Promotion Associates, Inc. • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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Peer-led program aims to cut HIV/STD risk in drug-using women
Prevention CompletedThis study tested whether a program designed specifically for women who use drugs could help them reduce their risk of HIV and other sexually transmitted diseases. 501 women were randomly assigned to receive either standard counseling, standard counseling plus a well-woman exam, …
Matched conditions: SUBSTANCE ABUSE
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Prevention
Last updated Jun 27, 2026 08:06 UTC
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Hospital study reveals who gets help for addiction in the ER
Knowledge-focused CompletedThis study looked back at the records of 652 patients who were seen in the emergency department of a French hospital and then referred to a special addiction liaison team. The goal was to understand the social and medical backgrounds of these patients. The findings could help hos…
Matched conditions: SUBSTANCE ABUSE
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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New study looks inside the womb to see how opioid medications impact unborn babies
Knowledge-focused CompletedThis study looked at pregnant women being treated for opioid use disorder with two different forms of buprenorphine: a monthly shot and a daily tablet. Researchers measured drug levels in the mother's blood and checked the baby's heart rate to see how each treatment affected both…
Matched conditions: SUBSTANCE ABUSE
Sponsor: T. John Winhusen, PhD • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Opioid treatment in pregnancy: which form is safer for Baby's brain?
Knowledge-focused CompletedThis study looked at 71 babies born to mothers who took either a monthly injection or a daily tablet of buprenorphine for opioid use disorder during pregnancy. Researchers measured the babies' thinking, language, and motor skills using a standard child development test. The goal …
Matched conditions: SUBSTANCE ABUSE
Sponsor: T. John Winhusen, PhD • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Vitiligo linked to higher risk of depression and anxiety in major study
Knowledge-focused CompletedThis study looked at over 36,000 adults in the UK to see if people with vitiligo are more likely to have mental health problems like depression, anxiety, or self-harm compared to those without vitiligo. Researchers used medical records to compare risks and also checked if these r…
Matched conditions: SUBSTANCE ABUSE
Sponsor: Momentum Data • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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AI could help hospitals identify hidden substance abuse
Knowledge-focused CompletedThis study developed a computer program that can scan hospital records to find patients who may be misusing drugs or alcohol. Researchers tested it on nearly 65,000 adults admitted to the hospital. The goal was to see if the tool could help doctors offer counseling and support to…
Matched conditions: SUBSTANCE ABUSE
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC