STAGE IVB HEPATOCELLULAR CARCINOMA AJCC V8
Clinical trials for STAGE IVB HEPATOCELLULAR CARCINOMA AJCC V8 explained in plain language.
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Tailored radiation beams aim to shrink untreatable liver tumors
Disease control OngoingThis study tests a personalized approach to radiation therapy for liver cancer patients whose tumors cannot be removed by surgery. By customizing the radiation dose for each person, researchers hope to improve tumor shrinkage while protecting healthy liver tissue. The trial invol…
Matched conditions: STAGE IVB HEPATOCELLULAR CARCINOMA AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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Immunotherapy duo after radiation shows promise for untreatable liver cancer
Disease control OngoingThis early-stage trial tests whether giving two immunotherapy drugs (durvalumab and tremelimumab) after a targeted radiation treatment can help control advanced liver cancer that cannot be removed by surgery. The study involves 25 adults with liver cancer that has spread locally.…
Matched conditions: STAGE IVB HEPATOCELLULAR CARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New combo shows promise for tough liver cancer
Disease control OngoingThis study tests a new drug called pevonedistat, given alone or with standard chemotherapy, in people with advanced bile duct cancer of the liver that has spread or cannot be removed. The goal is to see if the combination can shrink tumors. About 40 adults who have already tried …
Matched conditions: STAGE IVB HEPATOCELLULAR CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 12, 2026 12:05 UTC
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New combo aims to boost immune attack on tough liver cancers
Disease control OngoingThis early-phase trial tests a combination of two drugs (IRX-2 and nivolumab) plus a low-dose chemotherapy (cyclophosphamide) in 8 adults with advanced liver cancer that has returned or spread. The goal is to find the safest dose and see if the combo can help the immune system fi…
Matched conditions: STAGE IVB HEPATOCELLULAR CARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 03, 2026 12:04 UTC
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Home monitoring may keep cancer patients out of the ER
Symptom relief OngoingThis study tests whether using telemedicine and remote monitoring can help people with advanced digestive cancers manage chemotherapy side effects at home, reducing the need for emergency room visits and hospital stays. About 750 patients and their caregivers will receive enhance…
Matched conditions: STAGE IVB HEPATOCELLULAR CARCINOMA AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 16, 2026 22:37 UTC