STAGE IV PROSTATE ADENOCARCINOMA AJCC V7

This study looks at whether surgically removing the prostate, along with hormone therapy and possibly chemotherapy, can help men whose prostate cancer has already spread. About 190 men with newly diagnosed stage IV prostate cancer will be randomly assigned to get either standard …

This study tests whether adding cediranib to olaparib works better than olaparib alone for men with a hard-to-treat prostate cancer that has spread. About 90 men will take part. The goal is to see if the combination can slow cancer growth longer. Both drugs target cancer cells in…

This study tested whether adding a chemotherapy drug (cabazitaxel) to a hormone therapy (abiraterone) works better than hormone therapy alone for men with advanced prostate cancer that has spread and stopped responding to initial hormone treatment and a previous chemo drug (docet…

This study tested a treatment for men with prostate cancer that has spread to a few spots in the body (oligometastatic). It combined hormone therapy (drugs that lower male hormones) with a precise type of radiation aimed at the cancer spots. The goal was to see if this approach c…

This study is for men whose prostate cancer has returned after prostate removal surgery, shown by a rising PSA. It compares standard radiation therapy alone versus radiation plus a drug called apalutamide, which blocks male hormones that fuel cancer growth. The goal is to see if …

This study tests different combinations of approved drugs in 196 men with advanced prostate cancer that has spread and no longer responds to hormone therapy. The goal is to see which combinations work best to extend life and control the cancer. Participants receive standard hormo…