STAGE IIIA RECTAL CANCER AJCC V8
Clinical trials for STAGE IIIA RECTAL CANCER AJCC V8 explained in plain language.
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New drug combo aims to shrink rectal tumors with fewer side effects
Disease control OngoingThis early-stage study tests the safety of combining the chemotherapy drug TAS-102 with standard radiation for people with stage II or III rectal cancer that hasn't spread. The goal is to find the best dose that kills tumor cells while limiting side effects, before surgery to rem…
Matched conditions: STAGE IIIA RECTAL CANCER AJCC V8
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated May 17, 2026 08:16 UTC
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New hope for hard-to-treat colorectal cancer: drug duo targets tumor defenses
Disease control OngoingThis study tests a combination of two drugs—SX-682 and nivolumab—in people with a specific type of advanced colorectal cancer (RAS-mutated, MSS) that has spread or can't be removed. The goal is to see if the combination is safe and can shrink tumors or slow their growth. About 51…
Matched conditions: STAGE IIIA RECTAL CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 08:03 UTC
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New drug cocktail shows promise for Tough-to-Treat colorectal cancer
Disease control OngoingThis study tests whether adding two targeted drugs (LY3214996 and abemaciclib) to the standard drug cetuximab can shrink tumors or slow cancer growth in people with advanced colorectal cancer that no longer responds to cetuximab alone. About 46 adults with metastatic or inoperabl…
Matched conditions: STAGE IIIA RECTAL CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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The hidden cost of beating cancer: new study tracks financial toll on patients
Knowledge-focused OngoingThis study follows 565 people with stage I-III colon or rectal cancer who are being treated with the goal of a cure. Researchers track how treatment affects patients' finances and quality of life over 12 months. The goal is to help doctors understand the financial burden of cance…
Matched conditions: STAGE IIIA RECTAL CANCER AJCC V8
Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated May 17, 2026 08:03 UTC
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Blood tests could unlock secrets of rectal cancer
Knowledge-focused OngoingThis study looks at tiny pieces of cancer cells or DNA floating in the blood of people with rectal cancer. Researchers want to see if these "circulating tumor elements" can tell us how the cancer responds to standard treatment. They will also compare results from cancer patients …
Matched conditions: STAGE IIIA RECTAL CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC