STAGE III OVARIAN CANCER AJCC V8

This study aims to find out if a daily hormone pill (letrozole) works as well as or better than standard chemotherapy (paclitaxel/carboplatin) followed by the same pill for patients with advanced low-grade ovarian, fallopian tube, or peritoneal cancer. It involves 450 women who h…

This early-stage study is testing the safety and best dose of a new drug called ipatasertib when given alongside standard chemotherapy drugs (paclitaxel and carboplatin) to patients with advanced ovarian, fallopian tube, or primary peritoneal cancer. The goal is to see if adding …

This early-stage trial is testing a new drug called BAY 1895344, given alongside standard chemotherapy drugs, in people with advanced solid tumors that have spread. The main goal is to find the safest and most effective dose of this combination. Researchers are especially interes…

This is a small, early-stage safety study testing a combination of two cancer drugs, nivolumab and cabozantinib, in people living with HIV who have advanced solid tumors. The main goal is to see if the two-drug combination is safe and tolerable for this specific patient group. Re…

This study is testing a personalized treatment method for people with advanced breast, prostate, ovarian, pancreatic, or sarcoma cancers that have spread. Doctors analyze each patient's tumor using genetic and protein tests to understand how the cancer is changing and which drugs…

This early-stage trial is testing a combination of two drugs, niraparib and dostarlimab, for people with advanced breast, ovarian, pancreatic, or related cancers that have a specific genetic change (BRCA mutation) and have stopped responding to standard treatments. The goal is to…

This early study is testing whether a drug called olaparib can help shrink tumors before surgery in people newly diagnosed with advanced ovarian cancer that has a BRCA gene mutation. The trial involves about 15 participants who will take olaparib pills for up to two months before…

This study aimed to test an online mental health program designed to help women with advanced breast or gynecologic cancers manage their fear of the cancer coming back or getting worse. Participants would have been randomly assigned to either the main program, which taught coping…

This study is testing a new online program designed to help women with advanced gynecologic cancer manage their fear of the cancer getting worse or coming back. The program, called 'Day by Day,' teaches skills to handle anxiety and refocus thoughts. It is being tested with a smal…

This study aims to create a tool to predict which cancer patients are most likely to develop nerve damage (like tingling or numbness in hands and feet) from a common class of chemotherapy drugs called taxanes. Researchers will follow over 1,300 patients with breast, lung, or ovar…