STAGE IIC RECTAL CANCER AJCC V8
Clinical trials for STAGE IIC RECTAL CANCER AJCC V8 explained in plain language.
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New combo immunotherapy aims to shrink colon tumors before surgery
Disease control Recruiting nowThis study tests whether giving two immunotherapy drugs (botensilimab and balstilimab) before surgery can shrink tumors and improve outcomes for people with advanced colon cancer that can be removed. About 100 adults with stage IIB to IIIC colorectal cancer will receive the drugs…
Matched conditions: STAGE IIC RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jul 02, 2026 03:00 UTC
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Rectal cancer patients may skip surgery with chemo and watchful waiting
Disease control Recruiting nowThis early-phase trial is testing whether people with stage II-III rectal cancer can safely avoid surgery by first receiving chemotherapy and then being closely monitored. The goal is to see if the rectum can be preserved without harming survival. Around 120 participants will be …
Matched conditions: STAGE IIC RECTAL CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New combo therapy aims to save rectums from surgery
Disease control Recruiting nowThis early-phase trial tests whether a short course of radiation followed by chemotherapy can shrink advanced rectal tumors enough to avoid surgery. About 25 people with stage II or III rectal cancer will receive the treatment. The goal is to preserve the rectum and improve quali…
Matched conditions: STAGE IIC RECTAL CANCER AJCC V8
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New study tracks life after rectal cancer surgery
Knowledge-focused Recruiting nowThis study follows 430 people with stage I-IV rectal cancer to measure their quality of life after surgery. Participants fill out questionnaires about their well-being and daily function. The goal is to learn how surgery impacts patients over time, not to test a new treatment.
Matched conditions: STAGE IIC RECTAL CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Blood test may predict which rectal cancer patients can skip surgery
Knowledge-focused Recruiting nowThis study looks at whether a simple blood test can help doctors decide if rectal cancer patients can avoid surgery and keep their rectum. Researchers will measure tiny bits of tumor DNA in the blood (ctDNA) before, during, and after standard treatment. The goal is to see if chan…
Matched conditions: STAGE IIC RECTAL CANCER AJCC V8
Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC