STAGE IIB BREAST CANCER
Clinical trials for STAGE IIB BREAST CANCER explained in plain language.
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New chemo combo shows promise for tough breast cancer before surgery
Disease control OngoingThis study tested a two-drug chemotherapy combination (carboplatin and nab-paclitaxel) given before surgery to people with locally advanced or inflammatory triple negative breast cancer. The goal was to shrink tumors enough so that no cancer remains at the time of surgery (called…
Matched conditions: STAGE IIB BREAST CANCER
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 17, 2026 09:23 UTC
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New hope for tough breast cancer: which chemo works best after surgery?
Disease control OngoingThis study tests whether platinum-based chemotherapy (cisplatin or carboplatin) is better than capecitabine at preventing breast cancer from coming back in people with a specific type of triple-negative breast cancer (basal-like) that was not completely removed by initial chemoth…
Matched conditions: STAGE IIB BREAST CANCER
Phase: PHASE3 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 17, 2026 09:17 UTC
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New hope: Pre-Surgery combo shrinks breast tumors
Disease control OngoingThis study tested whether giving chemotherapy (paclitaxel and cyclophosphamide) with or without the targeted drug trastuzumab before surgery helps shrink breast cancer tumors in 92 women with early-stage or locally advanced breast cancer. The goal was to see if the treatment redu…
Matched conditions: STAGE IIB BREAST CANCER
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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One-Time radiation during breast surgery shows promise in Early-Stage cancer trial
Disease control OngoingThis study tests whether giving a single dose of electron beam radiation directly to the tumor cavity during breast-conserving surgery (lumpectomy) and before reconstruction can safely kill leftover cancer cells in women with early-stage breast cancer. About 108 participants with…
Matched conditions: STAGE IIB BREAST CANCER
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Shorter radiation after mastectomy may cut side effects and prevent cancer return
Disease control OngoingThis study tests whether a shorter course of radiation (hypofractionated) after mastectomy works as well as standard radiation to prevent breast cancer from coming back. About 900 women with stage II to IIIA breast cancer who had a mastectomy and reconstruction are taking part. T…
Matched conditions: STAGE IIB BREAST CANCER
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 11, 2026 20:40 UTC