STAGE II RECTAL CANCER AJCC V8
Clinical trials for STAGE II RECTAL CANCER AJCC V8 explained in plain language.
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New chemo cocktail may help rectal cancer patients skip surgery
Disease control OngoingThis study tests whether a three-drug chemotherapy combination (FOLFIRINOX) works better than standard two-drug combinations (FOLFOX or CAPOX) after radiation for stage II-III rectal cancer. The goal is to see if more patients can achieve a complete response, potentially avoiding…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Immunotherapy-Radiation combo shows promise against rectal cancer
Disease control OngoingThis study tests whether giving two immunotherapy drugs (nivolumab and ipilimumab) along with a short course of radiation can shrink advanced rectal tumors before surgery. About 31 adults with stage II or III rectal cancer that has a specific genetic feature (MSI-H/dMMR) will rec…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New hope: tailored therapy fights anal cancer in HIV patients
Disease control OngoingThis study tests a personalized approach for people with HIV who have anal cancer. Low-risk patients receive standard chemotherapy and radiation, while high-risk patients also get the immunotherapy drug nivolumab to help prevent the cancer from coming back. The goal is to see if …
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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The hidden cost of beating cancer: new study tracks financial toll on patients
Knowledge-focused OngoingThis study follows 565 people with stage I-III colon or rectal cancer who are being treated with the goal of a cure. Researchers track how treatment affects patients' finances and quality of life over 12 months. The goal is to help doctors understand the financial burden of cance…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated May 17, 2026 05:35 UTC