STAGE II RECTAL CANCER AJCC V8
Clinical trials for STAGE II RECTAL CANCER AJCC V8 explained in plain language.
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Immunotherapy combo aims to shrink rectal tumors before surgery
Disease control OngoingThis study is testing a new treatment approach for people with locally advanced rectal cancer that has a specific genetic marker (MSI-H/dMMR). The goal is to see if giving two immunotherapy drugs (nivolumab and ipilimumab) along with a short, intense course of radiation before su…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Stronger chemo cocktail tested to help rectal cancer patients avoid surgery
Disease control OngoingThis trial is testing whether a three-drug chemotherapy combination (FOLFIRINOX) works better than the standard two-drug combinations (FOLFOX or CAPOX) for patients with locally advanced rectal cancer. All patients first receive radiation with chemo, then are randomly assigned to…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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Tracking life after rectal cancer: how surgery affects daily living
Knowledge-focused TerminatedThis study aims to understand how rectal cancer surgery affects patients' quality of life over time. Researchers will follow 430 patients for up to 5 years after their surgery, asking them to complete questionnaires about their daily experiences. The goal is to gather information…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Cancer's hidden cost: study tracks financial toll on patients
Knowledge-focused OngoingThis study aims to understand how cancer treatment affects patients' finances and employment. Researchers are following 565 people with early-stage colon or rectal cancer for two years, asking them to complete surveys about costs, work life, and quality of life. The goal is to me…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC