SJOGREN'S DISEASE
Clinical trials for SJOGREN'S DISEASE explained in plain language.
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New drug aims to tame immune system in lupus and Sjogren's
Disease control Recruiting nowThis early-stage trial tests an investigational drug called ABBV-319 in 36 adults with lupus or Sjogren's disease. The drug is designed to deplete overactive B cells, which are part of the immune system that cause inflammation and symptoms. Participants receive two doses by IV, 2…
Matched conditions: SJOGREN'S DISEASE
Phase: PHASE1 • Sponsor: AbbVie • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Immune cell reprogramming offers hope for stubborn arthritis and Sjogren's
Disease control Recruiting nowThis early-phase study tests a personalized cell therapy (rapcabtagene autoleucel) in 27 adults with difficult-to-treat rheumatoid arthritis or severe Sjogren's disease. The treatment uses a patient's own immune cells, modified to target and calm the overactive immune system. The…
Matched conditions: SJOGREN'S DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Bone marrow cells injected into salivary glands to fight dry mouth
Symptom relief Recruiting nowThis early-phase trial tests whether injecting mesenchymal stromal cells (MSCs) into the salivary glands is safe and can ease dry mouth in people with graft-versus-host disease or Sjogren's disease. Up to 36 adults will receive one injection and be monitored for pain and side eff…
Matched conditions: SJOGREN'S DISEASE
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Scientists probe mystery of fatigue in Sjögren's patients
Knowledge-focused Recruiting nowThis study follows 100 adults with Sjögren's disease for 3 months to understand what causes their fatigue. Researchers will use questionnaires and pain tests to track fatigue, mood, sleep, and activity levels. The goal is to find factors that predict or explain fatigue, which cou…
Matched conditions: SJOGREN'S DISEASE
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC