SJÖGREN'S SYNDROME
Clinical trials for SJÖGREN'S SYNDROME explained in plain language.
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Experimental CAR-T injection aims to tame autoimmune diseases
Disease control Not yet recruitingThis early-phase trial tests an injection called KSVCBD, a type of CAR-T cell therapy, in 60 adults with severe autoimmune diseases like lupus and scleroderma. The goal is to see if it's safe and to get a first look at whether it might help control the disease. Participants recei…
Matched conditions: SJÖGREN'S SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Engineered immune cells take aim at autoimmune diseases
Disease control Not yet recruitingThis early study tests a new treatment called CD19/BCMA CAR-T for people with severe autoimmune diseases like lupus and Sjögren's syndrome that haven't improved with standard care. The treatment involves taking a patient's own immune cells, modifying them to target specific immun…
Matched conditions: SJÖGREN'S SYNDROME
Phase: NA • Sponsor: Shenzhen Genocury Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Stem cells injected twice may finally quench cancer survivors' dry mouth
Disease control Not yet recruitingThis study tests whether two doses of stem cells, given four months apart, can improve saliva production and reduce dry mouth in people who had radiation for head and neck cancer or have Sjögren's disease. One hundred participants will receive either stem cells or a placebo. The …
Matched conditions: SJÖGREN'S SYNDROME
Phase: PHASE2 • Sponsor: Christian von Buchwald • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Engineered immune cells take on lupus and other autoimmune diseases
Disease control Not yet recruitingThis early study tests a new treatment called CD19 UCAR-T cells for people with autoimmune diseases like lupus, vasculitis, and Sjögren's syndrome. The therapy uses modified immune cells to target and calm the overactive immune system. The main goals are to check safety and see i…
Matched conditions: SJÖGREN'S SYNDROME
Phase: NA • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New contact lens aims to soothe Sjögren's dry eye
Disease control Not yet recruitingThis early study tests a special contact lens (MSCohi-O) for people with Sjögren's syndrome whose dry eyes don't improve with standard treatments. Twelve participants will wear the lenses for 12 hours a day over 14 sessions. Researchers will check for side effects and measure cha…
Matched conditions: SJÖGREN'S SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Guangdong ProCapZoom Biosciences Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Could a simple ingredient boost dry eye drops?
Symptom relief Not yet recruitingThis study tests if adding sodium hyaluronate (a common moisturizer in artificial tears) to autologous serum eye drops provides better relief for moderate-to-severe dry eye disease. About 20 adults with dry eye from conditions like Sjögren's syndrome will use the new mix in one e…
Matched conditions: SJÖGREN'S SYNDROME
Phase: PHASE2 • Sponsor: University of Miami • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Can exosome eye drops soothe Sjögren's dry eyes?
Symptom relief Not yet recruitingThis early trial tests whether exosome eye drops can safely relieve dry eye symptoms in people with Sjögren's syndrome. Twelve adults whose dry eyes haven't improved with standard treatments will use the drops four times daily for two weeks. The main goal is to check for side eff…
Matched conditions: SJÖGREN'S SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Guangdong ProCapZoom Biosciences Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Blood test may predict Sjögren's severity
Knowledge-focused Not yet recruitingThis study looks at whether measuring a specific antibody, anti-Ro52, in the blood of people with Sjögren's syndrome can help predict who will develop serious problems like lymphoma or organ damage. Researchers will follow 150 patients over time to see if higher antibody levels a…
Matched conditions: SJÖGREN'S SYNDROME
Sponsor: Central Hospital, Nancy, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC