SEVERE TRAUMATIC BRAIN INJURY
Clinical trials for SEVERE TRAUMATIC BRAIN INJURY explained in plain language.
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One-Size-Fits-No-Brain: personalized ICU care tested
Disease control Not yet recruitingThis study tests whether setting a personalized 'optimal' blood pressure for each patient with severe traumatic brain injury reduces brain damage compared to standard fixed targets. Researchers will enroll 60 adults in the ICU and measure brain injury markers in the blood over fi…
Matched conditions: SEVERE TRAUMATIC BRAIN INJURY
Phase: NA • Sponsor: Maastricht University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Could a single dose of valproic acid help heal the brain after injury?
Disease control Not yet recruitingThis study tests whether a single dose of valproic acid, given soon after a moderate to severe traumatic brain injury, can improve patients' recovery and reduce disability. About 432 adults aged 18 to 65 will be randomly assigned to receive either valproic acid (at a low or high …
Matched conditions: SEVERE TRAUMATIC BRAIN INJURY
Phase: PHASE2, PHASE3 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Gut-Brain link after severe head injury: a new clue to preventing further damage
Knowledge-focused Not yet recruitingThis study investigates why severe traumatic brain injury (sTBI) often leads to additional brain damage. Researchers think changes in the gut and immune system may play a key role. They will analyze blood, stool, and other samples from 40 adults with sTBI, as well as from trauma …
Matched conditions: SEVERE TRAUMATIC BRAIN INJURY
Sponsor: Corewell Health West • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Brain injury registry aims to unlock secrets of recovery
Knowledge-focused Not yet recruitingThis study will collect detailed information from 200 adults with severe brain injuries treated at Örebro University Hospital. Researchers will track their recovery, including brain function and healthcare needs, for up to a year. No new treatments are being tested—the goal is to…
Matched conditions: SEVERE TRAUMATIC BRAIN INJURY
Sponsor: András Zoltán Buki • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC