SEVERE DEPRESSION
Clinical trials for SEVERE DEPRESSION explained in plain language.
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Could a headband at home keep depression away?
Disease control Recruiting nowThis pilot study tests whether a portable, at-home brain stimulation device (tDCS) can help people with depression maintain the improvements they achieved during hospital treatment with esketamine, rTMS, or ECT. Thirty adults will use the device for 30 minutes a day, five days a …
Matched conditions: SEVERE DEPRESSION
Phase: NA • Sponsor: Technical University of Munich • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Could a ketamine mist lift severe depression fast?
Symptom relief Recruiting nowThis study tests whether inhaling ketamine through a nebulizer can quickly reduce symptoms of moderate to severe depression in hospitalized adults. About 40 participants will receive either ketamine or a placebo (midazolam) and be monitored for changes in depression scores over 8…
Matched conditions: SEVERE DEPRESSION
Phase: PHASE3 • Sponsor: Theresa Jacob, PhD, MPH • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Music before and after ECT may soothe post-treatment agitation
Symptom relief Recruiting nowThis study tests whether listening to music before and after electroconvulsive therapy (ECT) can reduce postictal agitation—a common side effect where patients become restless or confused after treatment. Researchers will enroll 92 adults with severe depression undergoing ECT. Ha…
Matched conditions: SEVERE DEPRESSION
Phase: NA • Sponsor: Erasmus Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can a camera read your depression? new study aims to find out
Knowledge-focused Recruiting nowThis study will test if cameras, microphones, and wearable sensors can help doctors measure how severe a person's depression is. About 300 adults hospitalized for severe depression will be recorded during interviews and while wearing devices that track movement, heart rate, and b…
Matched conditions: SEVERE DEPRESSION
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC