RHABDOID TUMOR
Clinical trials for RHABDOID TUMOR explained in plain language.
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New drug targets tough childhood cancers with genetic flaws
Disease control CompletedThis phase 2 trial tested the drug samotolisib in 18 children and young adults with advanced solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that had spread, returned, or stopped responding to treatment. Only patients whose tumors had specific mutations in the TSC or…
Matched conditions: RHABDOID TUMOR
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New hope for kids with Hard-to-Treat cancers: targeted drug shows promise
Disease control CompletedThis study tested a drug called tazemetostat in 20 children whose cancers had come back or weren't responding to treatment. The children had specific gene changes (EZH2, SMARCB1, or SMARCA4) in their tumors. The goal was to see if the drug could shrink or slow the growth of these…
Matched conditions: RHABDOID TUMOR
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New stem cell transplant shows promise for kids with tough cancers
Disease control CompletedThis study tested a new way to do stem cell transplants in 23 children with cancers that came back or didn't respond to treatment. The method removes certain immune cells from the donor's stem cells to help the child's body recover faster and fight infections better. The goal was…
Matched conditions: RHABDOID TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Protein map of rare childhood cancer could reveal new attack points
Knowledge-focused CompletedThis study looked at protein patterns in tumor samples from 44 children with a rare cancer called rhabdoid tumor. Researchers used advanced techniques to see how tumors differ from each other. The goal was to find new targets for future treatments. The study is complete and did n…
Matched conditions: RHABDOID TUMOR
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Scientists map hidden diversity in rare childhood tumors
Knowledge-focused CompletedThis study looked at tumor samples from 15 children with rhabdoid tumors to understand why some parts of the tumor resist treatment. By analyzing individual cells, researchers aimed to identify different cell types within each tumor and find potential new targets for therapy. The…
Matched conditions: RHABDOID TUMOR
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC