RETINOBLASTOMA

This early-phase study tests a personalized cell therapy for children and young adults (up to age 26) with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, modified to recognize and attack a protein called B…

This early-stage study tests a treatment made from a patient's own immune cells, modified to recognize and attack solid tumors. It includes children and young adults (ages 1–30) whose cancer has returned or not responded to standard therapy. The goal is to find a safe dose and se…

This study tests whether chemotherapy followed by local treatments can control retinoblastoma (an eye cancer in children) and avoid removing the eye or using radiation. About 133 children with different stages of the disease will receive tailored drug regimens. The main goal is t…

This study looks at whether giving chemotherapy and, if needed, radiation after removing the eye can stop retinoblastoma from coming back in children. About 195 children with advanced retinoblastoma in one eye will receive this extra treatment based on how risky their tumor looks…

This study planned to see if a smartphone app called GoCheckKids could help find a white glow in children's eyes, which can be a sign of retinoblastoma, a rare eye cancer. The app was meant to be used from birth to age 10 to catch the disease early. However, the study was withdra…

This study examines how treatment for retinoblastoma (a rare eye cancer) and repeated general anesthesia impact thinking skills, emotional health, and quality of life in survivors aged 8 to 35. Researchers will test memory, attention, and other cognitive functions, and ask about …

This study follows 473 adults who had retinoblastoma (a rare eye cancer) as children, at least five years after treatment. Researchers want to understand their long-term health, including vision, second cancers, and quality of life. The goal is to improve care for future patients…