RESPIRATORY TRACT INFECTIONS

This study tests if bevacizumab, a drug that blocks blood vessel growth, can help adults with recurrent respiratory papillomatosis (RRP) go longer between surgeries to remove wart-like growths in their airways. About 21 participants who need at least two surgeries per year will r…

This study tests whether OM-85 (Broncho-Vaxom) can prevent respiratory infections in children aged 6 months to 5 years who have wheezing. About 525 children will receive either short-term OM-85, long-term OM-85, or a placebo. The goal is to see if OM-85 reduces the number of infe…

This study tracks 2,500 people and their dogs at four beaches in Ontario, Manitoba, and Nova Scotia to see how often they get sick from blue-green algae. Researchers will measure stomach bugs, skin rashes, eye infections, and breathing problems linked to swimming or playing in al…

This study aims to understand how the immune system responds to a second infection with a mild bird flu virus (H10N7). Healthy adults who were infected with H10N7 in a previous study will be infected again and monitored closely in the hospital for 9 days. The goal is to learn mor…

This study compares new, less invasive ways to collect samples for respiratory virus testing—like a nasal wash or saliva—against the standard deep nose swab. Researchers want to see if these gentler methods work just as well and cause less pain. About 1,000 adults in the emergenc…

This study is watching how infections like COVID-19 spread among people and between people and their pets in the Canton of Bern, Switzerland. Over 2,000 participants are providing samples and answering surveys to help scientists understand social and environmental factors that af…

This study tests three new types of pulse oximeters (devices that measure oxygen in the blood) for children under 2 years old with pneumonia in Cape Town, South Africa. The goal is to see if these devices help healthcare workers correctly identify low oxygen levels and refer chil…