REJECTION

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Trials to join now! 3 Not yet recruiting 1

Brain's own opioids may power placebo effect for heartbreak and pain

Knowledge-focused Not yet recruiting

This early-phase study investigates whether the opioid system is involved in placebo effects on both physical pain and the pain of social rejection. Sixty adults who recently experienced an unwanted breakup will receive either naloxone (which blocks opioids) or saline, and be tol…

Matched conditions: REJECTION

Phase: EARLY_PHASE1 • Sponsor: Trustees of Dartmouth College • Aim: Knowledge-focused

Last updated Jun 27, 2026 08:03 UTC

REJECTION

Get alerted when new REJECTION trials appear

Brain's own opioids may power placebo effect for heartbreak and pain