REFRACTORY PRIMARY MALIGNANT CENTRAL NERVOUS SYSTEM NEOPLASM
Clinical trials for REFRACTORY PRIMARY MALIGNANT CENTRAL NERVOUS SYSTEM NEOPLASM explained in plain language.
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New hope pill tested for kids with tough cancers
Disease control OngoingThis study is testing whether a pill called cabozantinib can help control rare cancers that have come back or stopped responding to other treatments in children and young adults. It includes patients with sarcomas, Wilms tumor, and other rare tumors. The drug aims to slow or stop…
Matched conditions: REFRACTORY PRIMARY MALIGNANT CENTRAL NERVOUS SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New hope for kids with deadly brain tumors: experimental therapy targets cancer directly in the brain
Disease control OngoingThis early-stage study is testing a new type of personalized immune cell therapy called SC-CAR4BRAIN for children and young adults with aggressive brain tumors that have come back or not responded to standard treatments. Doctors collect a patient's own immune cells, modify them i…
Matched conditions: REFRACTORY PRIMARY MALIGNANT CENTRAL NERVOUS SYSTEM NEOPLASM
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Targeted drug trial offers hope for kids with Tough-to-Treat cancers
Disease control OngoingThis study is testing an oral drug called ulixertinib in children and adolescents whose advanced cancers have not responded to standard treatments and have a specific genetic change in a cell pathway called MAPK. The main goal is to see if the drug can shrink tumors and control t…
Matched conditions: REFRACTORY PRIMARY MALIGNANT CENTRAL NERVOUS SYSTEM NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC