RECURRENT WHO GRADE 4 GLIOMA
Clinical trials for RECURRENT WHO GRADE 4 GLIOMA explained in plain language.
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New drug shows promise for tough brain cancers
Disease control Recruiting nowThis phase 2 trial tests the drug erdafitinib in 30 adults with a specific type of brain tumor (IDH-wild type glioma) that has come back or is getting worse. The tumor must have a certain gene fusion (FGFR-TACC). Erdafitinib blocks a faulty protein that helps cancer cells grow. T…
Matched conditions: RECURRENT WHO GRADE 4 GLIOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Engineered immune cells take on recurrent brain tumors in early trial
Disease control Recruiting nowThis early-phase trial is testing a new type of immunotherapy called anti-GARP CAR T-cell therapy for people with recurrent high-grade gliomas (aggressive brain tumors). Researchers will take a patient's own immune cells, modify them in the lab to target a protein called GARP fou…
Matched conditions: RECURRENT WHO GRADE 4 GLIOMA
Phase: PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Experimental drug combo takes on recurrent glioblastoma
Disease control Recruiting nowThis early-stage trial tests two drugs—triapine and temozolomide—together in people whose glioblastoma has returned. The goal is to find the safest dose and see how well patients tolerate the combination. About 30 adults with recurrent grade 2-4 glioma will take part.
Matched conditions: RECURRENT WHO GRADE 4 GLIOMA
Phase: PHASE1 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC