PRIMARY TOTAL KNEE ARTHROPLASTY
Clinical trials for PRIMARY TOTAL KNEE ARTHROPLASTY explained in plain language.
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Could a sedative drug extend pain relief after knee surgery?
Symptom relief CompletedThis study tested whether giving the sedative drug dexmedetomidine during knee replacement surgery could lengthen the time before patients need additional painkillers. 94 adults having elective knee replacement under regional anesthesia received either the drug or a placebo. The …
Matched conditions: PRIMARY TOTAL KNEE ARTHROPLASTY
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Knee replacement patients get extra pain relief from bone injection of morphine?
Symptom relief CompletedThis study tested whether adding morphine to a standard antibiotic injection into the shin bone during knee replacement surgery reduces pain afterward. About 100 adults having their first knee replacement took part. Half got morphine with the antibiotic, half got a placebo. Resea…
Matched conditions: PRIMARY TOTAL KNEE ARTHROPLASTY
Phase: PHASE2 • Sponsor: Carilion Clinic • Aim: Symptom relief
Last updated Jun 26, 2026 15:24 UTC