PRIMARY TOTAL KNEE ARTHROPLASTY
Clinical trials for PRIMARY TOTAL KNEE ARTHROPLASTY explained in plain language.
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Knee surgery pain relief gets a boost from sedative drug
Symptom relief CompletedThis study tested whether giving a drug called dexmedetomidine before knee replacement surgery could make pain relief from nerve blocks last longer. 94 adults having planned knee replacement took part. The goal was to see if the drug could delay the need for strong painkillers af…
Matched conditions: PRIMARY TOTAL KNEE ARTHROPLASTY
Phase: PHASE3 • Sponsor: CMC Ambroise Paré • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Knee replacement patients may get better pain relief with morphine in the bone
Symptom relief CompletedThis study tested whether adding morphine (a painkiller) to a standard antibiotic injection into the shin bone during knee replacement surgery helps reduce pain afterward. About 100 adults having their first knee replacement took part. Half got the antibiotic plus morphine, and h…
Matched conditions: PRIMARY TOTAL KNEE ARTHROPLASTY
Phase: PHASE2 • Sponsor: Carilion Clinic • Aim: Symptom relief
Last updated Apr 30, 2026 15:50 UTC