PRIMARY MEDIASTINAL B CELL LYMPHOMA
Clinical trials for PRIMARY MEDIASTINAL B CELL LYMPHOMA explained in plain language.
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New drug cocktail shows promise for tough blood cancers
Disease control CompletedThis study tested a new drug called MK-7684A, which combines two immune-boosting medicines (pembrolizumab and vibostolimab), in 192 people with blood cancers like lymphoma and multiple myeloma that had returned or stopped responding to prior treatments. The main goals were to see…
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Experimental Two-Pronged immune therapy tackles tough lymphoma
Disease control CompletedThis early-phase study tested a new cell therapy called C-CAR039 in 3 adults with B-cell non-Hodgkin's lymphoma that had come back or stopped responding to treatment. The therapy uses a patient's own immune cells, modified to target two proteins (CD19 and CD20) on cancer cells. T…
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Peking University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Radiation 'Re-Priming' could supercharge CAR-T therapy in stubborn lymphoma
Disease control CompletedThis study tested whether adding focused radiation to leftover cancer spots can improve outcomes for people with non-Hodgkin lymphoma whose tumors didn't fully respond to CAR-T cell therapy. Fourteen adults received radiation to those remaining areas. The goal was to see if this …
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Lymphoma Patients' brain function under microscope after new cell therapy
Knowledge-focused CompletedThis study followed 60 adults with diffuse large B-cell lymphoma or transformed lymphoma who received commercial axi-cel therapy. Researchers measured changes in memory, attention, executive function, hand strength, and quality of life using surveys and cognitive tests. The goal …
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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HIV Patients' CAR T-Cell cancer treatment under the microscope
Knowledge-focused CompletedThis study looked back at 30 people with HIV who received a special cancer treatment called CAR T-cell therapy for certain blood cancers. Researchers collected information from medical records to see what side effects occurred and how the immune system changed over time. The goal…
Matched conditions: PRIMARY MEDIASTINAL B CELL LYMPHOMA
Sponsor: AIDS Malignancy Consortium • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC