PRIMARY CNS LYMPHOMA
Clinical trials for PRIMARY CNS LYMPHOMA explained in plain language.
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Can engineered immune cells tackle brain lymphoma?
Disease control OngoingThis early-phase trial is testing a type of immunotherapy called CD19CAR T-cells in people aged 16 and older with relapsed or refractory primary CNS lymphoma, a rare cancer of the brain or spinal cord. The treatment involves collecting a patient's own immune cells, engineering th…
Matched conditions: PRIMARY CNS LYMPHOMA
Phase: PHASE1 • Sponsor: University College, London • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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New pill shows promise against rare brain cancer
Disease control OngoingThis phase 2 trial tests tirabrutinib, a targeted cancer pill, in 119 people with primary central nervous system lymphoma (PCNSL), a rare brain cancer. Part A looks at patients whose cancer has returned or not responded to prior treatment. Part B tests tirabrutinib combined with …
Matched conditions: PRIMARY CNS LYMPHOMA
Phase: PHASE2 • Sponsor: Ono Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New liquid biopsy could spot hidden brain lymphoma
Diagnosis OngoingThis study looks at whether a liquid biopsy (a simple test that checks for cancer DNA in spinal fluid) can better detect and monitor brain involvement in people with high-risk B-cell non-Hodgkin lymphoma. Researchers will compare this new method to standard tests in 64 newly diag…
Matched conditions: PRIMARY CNS LYMPHOMA
Phase: NA • Sponsor: Swiss Cancer Institute • Aim: Diagnosis
Last updated Jun 27, 2026 12:02 UTC