PRIMARY CILIARY DYSKINESIA
Clinical trials for PRIMARY CILIARY DYSKINESIA explained in plain language.
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Experimental mRNA inhalation therapy targets rare lung disease
Disease control CompletedThis early-phase study tests an inhaled mRNA therapy called RCT1100 in 7 adults with primary ciliary dyskinesia caused by DNAI1 gene mutations. The goal is to see if the treatment is safe and can help restore ciliary function in the lungs. It is a small, open-label trial focused …
Matched conditions: PRIMARY CILIARY DYSKINESIA
Phase: PHASE1 • Sponsor: ReCode Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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NIH study aims to unlock secrets of lung mucus diseases
Knowledge-focused CompletedThis completed study looked at people with genetic conditions that affect how the lungs clear mucus, such as cystic fibrosis and primary ciliary dyskinesia. Researchers examined 87 participants, including healthy volunteers, to understand why these patients get repeated lung infe…
Matched conditions: PRIMARY CILIARY DYSKINESIA
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:08 UTC
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Rare lung disease study aims to uncover key health markers
Knowledge-focused CompletedThis completed study observed 31 adults with primary ciliary dyskinesia (PCD), a rare lung condition, along with healthy volunteers. Researchers measured lung function, mucus clearance, and lung structure using tests like spirometry and CT scans. The goal was to better understand…
Matched conditions: PRIMARY CILIARY DYSKINESIA
Sponsor: ReCode Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Study aims to map respiratory attacks in rare lung disease
Knowledge-focused CompletedThis completed study followed 105 children and adults with primary ciliary dyskinesia (PCD), a rare lung condition, to track how their breathing and quality of life change during respiratory flare-ups. Researchers measured lung function, symptoms, and daily impacts to gather info…
Matched conditions: PRIMARY CILIARY DYSKINESIA
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Gene clues may predict lung function in rare disease
Knowledge-focused CompletedThis study looked at how well people with Primary Ciliary Dyskinesia (PCD) clear mucus from their lungs, based on which gene mutation they have. Researchers measured lung clearance in 27 participants, including healthy volunteers and PCD patients with different genetic mutations.…
Matched conditions: PRIMARY CILIARY DYSKINESIA
Phase: EARLY_PHASE1 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:24 UTC