PRIMARY BRAIN TUMOR
Clinical trials for PRIMARY BRAIN TUMOR explained in plain language.
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New hope for kids with resistant tumors: drug combo enters safety trial
Disease control OngoingThis early-stage study tests a combination of two drugs, avutometinib and defactinib, in children and young adults (ages 3 to 30) with advanced or recurrent solid tumors that have specific genetic changes. The main goal is to find the safest dose with the fewest side effects. The…
Matched conditions: PRIMARY BRAIN TUMOR
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a common antidepressant boost brain tumor treatment?
Knowledge-focused OngoingThis early-phase trial tests whether fluoxetine, an FDA-approved antidepressant, can increase stress in cell structures called lysosomes to make the chemotherapy drug temozolomide more effective against recurrent brain tumors. Ten participants with recurrent glioma will receive e…
Matched conditions: PRIMARY BRAIN TUMOR
Phase: EARLY_PHASE1 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC