PREMATURE BIRTH
Clinical trials for PREMATURE BIRTH explained in plain language.
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Skin-to-Skin care may boost survival in tiny newborns
Disease control CompletedThis study looked at whether starting kangaroo mother care (skin-to-skin contact and breastfeeding support) within the first 24 hours helps healthy preterm babies born weighing less than 2000 grams. 100 infants were randomly assigned to early kangaroo care or standard care. Resea…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: University of Health Sciences Lahore • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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Pessary or progesterone: which better prevents preterm birth?
Prevention CompletedThis study tested whether a silicone vaginal pessary or natural progesterone is better at preventing early birth in pregnant women whose cervix is 25 mm or shorter. 203 women with a single baby between 20 and 24 weeks of pregnancy took part. The goal was to see which treatment re…
Matched conditions: PREMATURE BIRTH
Phase: PHASE4 • Sponsor: University of Sao Paulo • Aim: Prevention
Last updated Jun 16, 2026 12:52 UTC
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Which progesterone works best to stop preterm birth?
Prevention CompletedThis study tested two forms of progesterone—vaginal gel and intramuscular shots—to see which better prevents another early birth in women who have already had a preterm baby. 210 pregnant women with a prior preterm birth took part. The goal was to find if the vaginal form is more…
Matched conditions: PREMATURE BIRTH
Phase: PHASE4 • Sponsor: Thomas Jefferson University • Aim: Prevention
Last updated Jun 15, 2026 19:03 UTC
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Group prenatal care shows promise for reducing preterm birth in pacific islander community
Prevention CompletedThis study tested whether a group-based prenatal program called Centering Pregnancy, combined with a care navigator, could improve pregnancy outcomes for Marshallese women. 38 pregnant women participated, and researchers looked at rates of preterm birth, low birthweight, and C-se…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: University of Arkansas • Aim: Prevention
Last updated Jun 12, 2026 12:04 UTC
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VR headsets boost breast milk in preemie moms, study finds
Symptom relief CompletedThis study tested whether using virtual reality (VR) for relaxation helps mothers of premature babies produce more breast milk and feel more confident about breastfeeding. 44 first-time mothers with babies in the NICU either watched calming VR nature videos before expressing milk…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Kocaeli University • Aim: Symptom relief
Last updated Jun 10, 2026 13:25 UTC
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Soothing sounds: music therapy may help preterm babies and parents
Symptom relief CompletedThis study looked at whether music therapy can help preterm babies in the NICU and their caregivers. Researchers measured babies' vital signs like heart rate and breathing, as well as caregiver wellbeing. The goal was to gather initial UK evidence to support wider use of this gen…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Anglia Ruskin University • Aim: Symptom relief
Last updated Jun 05, 2026 12:07 UTC
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Massive study reveals hidden delays in sending preemies home
Knowledge-focused CompletedThis study looked at medical records of 250,000 preterm babies born in England and Wales to find out when they become healthy enough to leave the hospital. Researchers tracked when each baby could breathe on their own, eat by mouth, and reach a healthy weight. They also measured …
Matched conditions: PREMATURE BIRTH
Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 16, 2026 22:21 UTC
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Mom's voice may boost preemie brain growth
Knowledge-focused CompletedThis study tested whether playing recordings of a mother's voice to preterm babies in the NICU helps their brain and language development. Researchers enrolled 57 preterm infants born between 24 and 31 weeks. The goal was to see if this simple, non-invasive intervention could imp…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 16, 2026 22:21 UTC
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New device could help protect tiny Babies' brains
Knowledge-focused CompletedThis study tested a new, safe way to monitor brain health in 100 extremely premature babies (born before 29 weeks). The device uses light to measure blood flow and oxygen use in the brain. Researchers hope this will help doctors spot problems early and improve care for these frag…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Maria Angela Franceschini • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:09 UTC
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Premature baby breathing study completed: no new treatment, just observation
Knowledge-focused CompletedThis study looked at how premature babies (born before 37 weeks) respond to different types of breathing support, like CPAP or high-flow nasal cannula. Researchers tracked how long babies needed support and checked for lung problems. The goal was to gather information, not to tes…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC
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Car seat safety check for tiny lungs: study measures breathing in preterm infants
Knowledge-focused CompletedThis study looked at how lung volume changes when stable preterm babies are placed in car seats. Using a special imaging technique, researchers measured breathing in 51 infants born before 37 weeks. The goal was to understand if the semi-upright car seat position affects lung aer…
Matched conditions: PREMATURE BIRTH
Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:04 UTC
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Can a website and phone calls help parents of preemie toddlers?
Knowledge-focused CompletedThis study looked at whether a web-based parent training program, with or without telephone coaching, helps parents of toddlers born very premature. About 220 parents took part and were split into four groups to compare the effects on parenting skills and child behavior over a ye…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:03 UTC
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Breast milk showdown: natural vs. pasteurized for tiny preemies
Knowledge-focused CompletedThis study looked at whether natural (unprocessed) milk or pasteurized milk helps the gut mature faster in very premature babies born between 28 and 30 weeks. Fifty-five infants were given small amounts of either natural or pasteurized milk to see how their digestive systems resp…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC
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South african study links vaginal infections to early births
Knowledge-focused CompletedThis study looked at 603 pregnant women in South Africa to see if infections in the genital tract are linked to giving birth earlier. Researchers tested for various germs and yeast at the start of pregnancy and again later. The goal was to understand which infections or combinati…
Matched conditions: PREMATURE BIRTH
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:09 UTC
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Parents' feeding role may boost time with preemies
Knowledge-focused CompletedThis study tested if having parents control a syringe to feed their premature baby (instead of using a machine) encourages them to spend more time in the neonatal unit. It involved 72 premature infants born between 30 and 34 weeks. The main goal was to compare how many hours pare…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:26 UTC
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Could feeding past the stomach help tiny preemies breathe easier?
Knowledge-focused CompletedThis study looked at whether feeding very low birth weight premature babies directly into the small intestine (duodenum) is safe and doable. The goal is to reduce stomach reflux that can worsen lung damage. 24 infants were enrolled to test tube placement success and check for com…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Johns Hopkins All Children's Hospital • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:17 UTC