PLAQUE
Clinical trials for PLAQUE explained in plain language.
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New toothpaste fights gum disease in 12-Week trial
Disease control CompletedThis study tested whether a stannous fluoride toothpaste can reduce gum inflammation, bleeding, and plaque better than a standard fluoride toothpaste. Over 12 weeks, 133 adults brushed with one of the two toothpastes and had their gums checked at several visits. The goal was to s…
Matched conditions: PLAQUE
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Toothpaste and mouthwash combo takes on plaque in new study
Disease control CompletedThis study tested whether using a stannous fluoride toothpaste, a cetylpyridinium chloride mouthwash, and a battery-powered toothbrush together can reduce dental plaque and gingivitis (gum inflammation). 134 adults with at least 20 teeth and signs of gum disease used the regimen …
Matched conditions: PLAQUE
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New toothpaste and brush combo fights plaque and gum disease in 3-Month trial
Disease control CompletedThis study compared a stannous fluoride toothpaste paired with a newly designed toothbrush to a standard toothpaste and brush for reducing plaque and gingivitis (gum inflammation). 95 adults with mild to moderate gum issues used their assigned products for 3 months. Researchers m…
Matched conditions: PLAQUE
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New toothpaste and mouthwash combo takes on plaque and gingivitis
Disease control CompletedThis study tested whether using a stannous fluoride toothpaste along with a cetylpyridinium chloride mouthwash and a manual toothbrush reduces dental plaque and gingivitis better than using regular fluoride toothpaste with a standard toothbrush. Eighty-two adults with mild gum di…
Matched conditions: PLAQUE
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Battery toothbrush beats manual in gum health showdown
Disease control CompletedThis completed Phase 3 study tested whether a battery toothbrush paired with a stannous fluoride toothpaste is more effective at reducing plaque and gingivitis than a regular fluoride toothpaste with a manual toothbrush. 130 adults with mild gum disease brushed twice daily for 12…
Matched conditions: PLAQUE
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New app and video program aims to make brushing fun for tots
Prevention CompletedThis study tested a program called BeReady2Smile (BR2S) that uses videos and a mobile app to teach parents how to brush their young children's teeth and prevent cavities. 228 families with kids aged 0-6 took part. The goal was to see if the program improves parents' brushing habi…
Matched conditions: PLAQUE
Phase: NA • Sponsor: Oregon Research Behavioral Intervention Strategies, Inc. • Aim: Prevention
Last updated Jun 27, 2026 07:53 UTC
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New toothbrush aims to zap gingivitis in one go
Symptom relief CompletedThis study tested a full-mouth electronic toothbrush (FMET) to see if it reduces gum inflammation and plaque better than a regular electronic toothbrush. 94 adults with mild to moderate gingivitis used either the FMET, a conventional electronic toothbrush, or the FMET with a spec…
Matched conditions: PLAQUE
Phase: NA • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC